Drospirenone

IUPAC Name: (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-hexadecahydro-10,13-dimethylspiro-[17H-dicyclopropa-6,7:15,16]cyclopenta[a]phenanthrene-17,2'(5H)-furan]-3,5'(2H)-dione)
Molecular Formula: C₂₄H₃₀O₃
Molecular Weight: 366.49 g/mol
SMILES: O1C(CC[C@]21[C@@H]1[C@@H]([C@H]3[C@@H]4[C@@H]5[C@@H](C5)C5=CC(=O)CC[C@@]5([C@H]4CC[C@@]23C)C)C1)=O
InChI: InChI=1/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
EINECS: 266-679-2
Classification Code: Aldosterone antagonist; Aldosterone antagonists; Hormone; Hormone Antagonists; Hormones, Hormone Substitutes, and Hormone Antagonists; Reproductive Effect
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Steroids
Index of Refraction: 1.61 
Molar Refractivity: 100.4 cm³ 
Molar Volume: 289.4 cm³ 
Polarizability: 39.8×10^-24 cm³ 
Surface Tension: 51.2 dyne/cm 
Density: 1.26 g/cm³ 
Flash Point: 241.6 °C 
Enthalpy of Vaporization: 83.27 kJ/mol 
Boiling Point: 552.2 °C at 760 mmHg 
Melting Point: 196-200 °C
alpha: -180 °(c=0.5, chloroform)
Vapour Pressure of Drospirenone (CAS NO.67392-87-4): 3.07E-12 mmHg at 25 °C

 Drospirenone (CAS NO.67392-87-4) is used as synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity.

  Drospirenone (CAS NO.67392-87-4), its Synonyms are 1,2-Dihydrospirorenone ; 6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione ; 17-Hydroxy-6beta,7beta:15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone ; 6-beta,7-beta;15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone ; Drospirenona . It is off-white crystalline powder.