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Duloxetine |
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IUPAC Name: (3S)-N-Methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
Synonyms of Duloxetine (CAS NO.116539-59-4) : (+)-(S)-N-methyl-g-(1-naphthyloxy)-2-thiophenepropylamine ; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine ; (S)-N-Methyl-g-(1-naphthalenyloxy)-2-thiophenepropanamine ; 2-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, (gammaS)- ; Cymbalta
InChI:InChI=1/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1
CAS NO:116539-59-4
Molecular Formula:C18H19NOS
Molecular Weight :297.4146
Molecular Structure :
Index of Refraction: 1.627
Surface Tension: 46 dyne/cm
Density: 1.158 g/cm3
Flash Point: 235.7 °C
Enthalpy of Vaporization: 72.79 kJ/mol
Boiling Point: 466.2 °C at 760 mmHg
Vapour Pressure: 7.23E-09 mmHg at 25°C
Duloxetine (CAS NO.116539-59-4) is a serotonin-norepinephrine reuptake inhibitor,It is effective for major depressive disorder and it is as effective as venlafaxine in generalized anxiety disorder.Duloxetine alleviates pain associated with diabetic neuropathy and fibromyalgia; however, its efficacy relative to the established treatments, such as anticonvulsants and tricyclic antidepressants, has not been studied.
Nausea, somnolence, insomnia, and dizziness are the main side effects of Duloxetine (CAS NO.116539-59-4), reported by about 10% to 20% of patients