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Basic information

  • Name:
  • Febuxostat

  • CAS No.:
  • 144060-53-7

  • Molecular Structure:
  • Formula:
  • C16H16N2O3S
  • Molecular Weight:
  • 316.3748
  • Synonyms:
  • 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-;Tei 6720;Febuxostat/ 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat (JAN/USAN);TMX 67;Tei-6720;2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;TMX-67;
  • Density:
  • 1.31 g/cm3
  • Melting Point:
  • 238-239 °C
  • Boiling Point:
  • 536.6 °C at 760 mmHg
  • Flash Point:
  • 278.3 °C
  • Appearance:
  • crystalline solid

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Chemistry

IUPAC Name: 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Synonyms of Febuxostat (CAS NO.144060-53-7): 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid ; 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
CAS NO: 144060-53-7
Molecular Formula: C16H16N2O3S
Molecular Weight: 316.37
Molecular Structure:
H bond acceptors: 5
H bond donors: 1
Freely Rotating Bonds: 5
Polar Surface Area: 100.45 Å2
Index of Refraction: 1.605
Molar Refractivity: 83.09 cm3
Molar Volume: 240.9 cm3
Surface Tension: 63.7 dyne/cm
Density: 1.31 g/cm3
Flash Point: 278.3 °C
Enthalpy of Vaporization: 85.6 kJ/mol
Boiling Point: 536.6 °C at 760 mmHg
Vapour Pressure: 2.41E-12 mmHg at 25°C 
Melting Point: 238-239°(dec.)
Appearance: Crystalline Solid
Product Categories of Febuxostat (CAS NO.144060-53-7): Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals

Uses

 Febuxostat (CAS NO.144060-53-7) is an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuricemia and gout.

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