Monatshefte fur Chemie p. 1237 - 1254 (1984)
Update date:2022-08-04
Topics:
Brunner, Henri
Miehling, Wolfgang
Copper(II) compounds catalyze the reaction of 1,1-diphenylethylene with diazoacetic acid ethylester.The main product is 2,2-diphenylcyclopropane carboxylic acid ethylester.The formation of the carbene dimerization products fumaric and maleic acid diethylester can be suppressed by the continuous addition of diazoacetic ester to 1,1-diphenylethylene. 37 optically active ligands, partly new, were combined with copper(II)-acetate to give in-situ-catalysts.In five cases isolated copper complexes were used as catalysts.The best optical inductions in the formation of 2,2-diphenylcyclopropane carboxylic acid ethylester with up to 65.6percent ee were achived with Schiffbase ligands, which derive from salicylaldehyde and amino alcohols, obtained from amino acid esters and phenyl Grignard. - Keywords: Catalytic enantioselective cyclopropanation; Copper(II) catalysts; Optical induction.
View Morewebsite:http://www.gihichemicals.com
Contact:+86-571-86217390
Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Beijing Mediking Biopharm Co., Ltd.
Contact:+86-10-89753524/81760121/81769521
Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
Hangzhou Mole's Science & Technology Co.,Ltd.
Contact:+86-571-56880228
Address:15F Guodu development Building, NO.182 Zhaohui Road
website:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Contact:+86-25-52346955
Address:199,JIANYE ROAD,NANJING,CHINA
Doi:10.1007/BF00954118
(1984)Doi:10.1002/jhet.5570210545
(1984)Doi:10.1039/c6ob02655a
(2017)Doi:10.1107/S0108270106010833
(2006)Doi:10.1007/s00706-006-0558-1
(2007)Doi:10.1016/j.jorganchem.2007.06.027
(2007)