- Histamine
- Histamine dihydrochloride
- Histamine diphosphate
- Histamine phosphate
- 51742-11-12-Cyclohexen-1-one,6-acetyl-3-methyl-
- 51742-42-8(Z)-3-bromo-2-chloro-4-oxo-but-2-enoic acid
- 5174-32-3Phenol,2-(chloromethyl)-4-nitro-, acetate (ester) (9CI)
- 517-44-2[9,9'-Bianthracene]-2,2'-dicarboxylicacid, 9,9',10,10'-tetrahydro-4,4',5,5'-tetrahydroxy-10,10'-dioxo-,(9R,9'S)-rel-
- 517-45-39H-Xanthene,9-(9H-xanthen-9-ylidene)-
- 51746-81-7Ethanone,2-amino-1-(2-pyridinyl)-, hydrochloride (1:2)
- 51746-85-1Pyridine,3-(1H-imidazol-5-yl)-
- 5174-90-31,8-Naphthyridine-3-carboxylicacid, 1,2-dihydro-2-oxo-, ethyl ester
- 51749-29-2p-Decyloxybenzylidene p-butylaniline
- 51749-83-8Anthracene,1,8-dichloro-9,10-bis(2-phenylethynyl)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
Histamine phosphate |
EINECS | 200-118-4 |
| CAS No. | 51-74-1 | Density | N/A |
| PSA | 142.27000 | LogP | -0.31740 |
| Solubility | Soluble in water. | Melting Point |
128-132°C |
| Formula | C5H9N3.2(H3PO4) | Boiling Point | 331 °C at 760 mmHg |
| Molecular Weight | 307.13 | Flash Point | 180.3 °C |
| Transport Information | N/A | Appearance | White crystal powder |
| Safety | 26-36-45-36/37/39-22 | Risk Codes | 20/21/22-36/37/38-42/43-41-37/38-22 |
| Molecular Structure |
|
Hazard Symbols | Xn |
| Synonyms |
Histamine acid phosphate;1H-Imidazole-4-ethanamine,compounds,phosphate (1:2);Histamine Diphosphate;Histamine bisphosphate monohydrate; |
Histamine phosphate Chemical Properties
Molecular Structure of Histamine phosphate (CAS NO.51-74-1):
.png)
Molecular Formula C5H9N3.2(H3PO4)
Molecular Weight 307.13
IUPAC Name: 2-(1H-Imidazol-5-yl)ethanamine; phosphoric acid
Synonyms of Histamine phosphate (CAS NO.51-74-1): Histamine phosphate [USP] ; 4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate) ; 4-(2-Aminoethyl)imidazole di-acid phosphate ; EINECS 200-118-4 ; Histamine acid phosphate ; Histamine biphosphate ; Histamine dihydrogen phosphate ; Histamine diphosphate ; Histamine phosphate (1:2) ; Histamine positive ; UNII-QWB37T4WZZ ; 1H-Imidazole-4-ethanamine, phosphate (1:2) ; 2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
CAS NO: 51-74-1
Classification Code: Histamine Agents ; Neurotransmitter Agents ; Reproductive Effect ; Stimulant [gastric secretory] Stimulant [gastric secretory]
Flash Point: 180.3 °C
Enthalpy of Vaporization: 57.36 kJ/mol
Boiling Point: 331 °C at 760 mmHg
Vapour Pressure: 0.00016 mmHg at 25°C
nChI
InChI=1/C5H9N3.2H3O4P/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4)
Download | View Full InChI
Smiles
[nH]1cnc(CCN)c1.P(O)(=O)(O)O.P(O)(=O)(O)O
Classification Code: Histamine Agents; Neurotransmitter Agents; Reproductive Effect; Stimulant
Histamine phosphate Uses
Histamine phosphate (CAS NO.51-74-1) has been used for the presumptive diagnosis of pheochromocytoma; however, the use of histamine in patients suspected of having pheochromocytoma is hazardous and unwarranted due to the risk of precipitating a hypertensive crisis. Histamine phosphate has been used to produce short-term improvement in patients with vertigo, tinnitus, and deafness. However, it has not been proven effective in the symptomatic treatment of Menière's disease.
Histamine phosphate Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intravenous | 608ug/kg (0.608mg/kg) | LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION | Journal of Pharmaceutical Sciences. Vol. 57, Pg. 1543, 1968. |
| guinea pig | LDLo | parenteral | 746ug/kg (0.746mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1574, 1970. | |
| mouse | LD50 | intraperitoneal | 913mg/kg (913mg/kg) | Journal of Pharmaceutical Sciences. Vol. 59, Pg. 1659, 1970. | |
| mouse | LD50 | intravenous | 333mg/kg (333mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 90, Pg. 726, 1955. | |
| mouse | LD50 | oral | 807mg/kg (807mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 122, Pg. 685, 1966. | |
| rabbit | LD50 | intravenous | 2763ug/kg (2.763mg/kg) | BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 299, 1942. |
| rabbit | LDLo | parenteral | 1mg/kg (1mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925. |
| rat | LD50 | intraperitoneal | 1781mg/kg (1781mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 119, Pg. 444, 1957. | |
| rat | LDLo | intravenous | 900mg/kg (900mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925. |
Histamine phosphate Consensus Reports
Reported in EPA TSCA Inventory.
Histamine phosphate Safety Profile
A deadly poison by intravenous and parenteral routes. Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and POx.
What can I do for you?
Get Best Price
