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Hydroquinidine hydrochloride

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Name

Hydroquinidine hydrochloride

EINECS 216-024-1
CAS No. 1476-98-8 Density 1.2 g/cm3
PSA 45.59000 LogP 4.13710
Solubility almost transparency in hot Water Melting Point 277-279 °C(lit.)
Formula C20H27ClN2O2 Boiling Point 522.1 °C at 760 mmHg
Molecular Weight 362.9 Flash Point 269.6 °C
Transport Information 1544 Appearance N/A
Safety 36 Risk Codes 22-20/21/22
Molecular Structure Molecular Structure of 1476-98-8 (HYDROQUINIDINE HYDROCHLORIDE) Hazard Symbols HarmfulXn
Synonyms

Hydroquindine Hydrochloride;Dihydroquinidine Hydrochloride;Hydroquinidine Hydrochloride;Hydroquinidine HCl;hydroquinidine,monohydrochloride;Einecs 216-024-1;dihydrochinidinhydrochlorid;

 

Hydroquinidine hydrochloride Specification

This chemical is called Hydroquinidine hydrochloride, and its systematic name is (9S)-6'-methoxy-10,11-dihydrocinchonan-9-ol hydrochloride. With the CAS registry number of 1476-98-8, its product categories are Alkaloids; Alkoxyquinolines; Biochemistry; for Resolution of Acids; Optical Resolution; Quinoline Alkaloids; Synthetic Organic Chemistry. In addition, this chemical should be sealed in the cool and dry place, away from oxides.

Other characteristics of the Hydroquinidine hydrochloride can be summarised as followings: (1)ACD/LogP: 3.77; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 4; (4)#H bond donors: 1; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 34.59 Å2; (7)Flash Point: 269.6 °C; (8)Enthalpy of Vaporization: 83.75 kJ/mol; (9)Boiling Point: 522.1 °C at 760 mmHg; (10)Vapour Pressure: 9.92E-12 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following: This chemical is harmful by inhalation, in contacting with skin and if swallowed. Wear suitable protective clothing if you use it.

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intraperitoneal > 100mg/kg (100mg/kg)   Cancer Research. Vol. 52, Pg. 2797, 1992.
Link to PubMed
rat LD intraperitoneal > 100mg/kg (100mg/kg)   Cancer Research. Vol. 52, Pg. 2797, 1992.
Link to PubMed
rat LD50 intravenous 32mg/kg (32mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 589, 1977.
Link to PubMed
rat LD50 oral 369mg/kg (369mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 589, 1977.
Link to PubMed

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