IUPAC Name: N-[2-[[2-[[2-[[2-[[2-[[1-[[1-[2-[(2-Amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-guanidino-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-1-(3H-imidazol-4-ylmethyl)-2-oxo-ethyl]-5-oxo-pyrrolidine-2-carboxamide
Index of Refraction: 1.713 
EINECS: 254-420-6
Density: 1.54 g/ml 
Storage temp: 2-8 °C
Form: lyophilized powder

 In the male, Luteinizing hormone (human) (CAS NO.39341-83-8) acts upon the Leydig cells of the testis and is responsible for the production of testosterone, an androgen that exerts both endocrine activity and intratesticular activity on spermatogenesis.
 In females, at the time of menstruation, FSH initiates follicular growth, specifically affecting granulosa cells. With the rise in estrogens, LH receptors are also expressed on the maturing follicle that produces an increasing amount of estradiol. Eventually at the time of the maturation of the follicle, the estrogen rise leads via the hypothalamic interface to the “positive feed-back” effect, a release of LH over a 24-48 hour period. This 'LH surge' triggers ovulation thereby not only releasing the egg, but also initiating the conversion of the residual follicle into a corpus luteum that, in turn, produces progesterone to prepare the endometrium for a possible implantation. LH is necessary to maintain luteal function for the first two weeks. In case of a pregnancy luteal function will be further maintained by the action of hCG (a hormone very similar to LH) from the newly established pregnancy. LH supports thecal cells in the ovary that provide androgens and hormonal precursors for estradiol production.

Safety information of Luteinizing hormone (human) (CAS NO.39341-83-8):
Hazard Codes:  T,B
Risk Statements: 
R60: May impair fertility
Safety Statements: 
S53: Avoid exposure - obtain special instruction before use
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
WGK Germany: 3
RTECS: OK6367000

  Luteinizing hormone (human) levels are normally low during childhood and, in women, high after menopause. As Luteinizing hormone (human) is secreted as pulses, it is necessary to follow its concentration over a sufficient period of time to get a proper information about its blood level.
 During the reproductive years typical levels are between 1-20 IU/L. Physiologic high LH levels are seen during the Luteinizing hormone (human) surge (v.s.); typically they last 48 hours.

  Luteinizing hormone (human) can be detected by urinary ovulation predictor kits (OPK, also LH-kit) that are performed, typically daily, around the time ovulation may be expected. The conversion from a negative to a positive reading would suggest that ovulation is about to occur within 24–48 hours, giving women two days to engage in sexual intercourse or artificial insemination with the intentions of conceiving.
 Tests may be read manually using a colour-change paper strip, or digitally with the assistance of reading electronics.
 Tests for Luteinising hormone may be combined with testing for estradiol in tests such as the Clearblue fertility monitor.
 The sensitivity of LH tests are measured in milli international unit, with tests commonly available in the range 10-40 m.i.u.
 As sperm can stay viable in the woman for several days, LH tests are not recommended for contraceptive practices, as the LH surge typically occurs after the beginning of the fertile window.

  Luteinizing hormone (human) (CAS NO.39341-83-8), its Synonyms are Luteinizing hormone ; Luteinizing hormone, human ; Luteinizing hormone, human pituitary ; LH ; LH, human pituitary ; Icsh ; HLH ; PLH .