- 487-70-7Benzaldehyde,2,4,6-trihydroxy-
- 4877-14-9Tetradecane,1-isocyanato-
- 4877-93-41,1'-Biphenyl,2,2'-dimethoxy-
- 487-79-63-Pyrrolidineaceticacid, 2-carboxy-4-(1-methylethenyl)-, (2S,3S,4S)-
- 487-89-8Indole-3-carboxaldehyde
- 487-93-41H-Indol-5-ol,3-[2-(dimethylamino)ethyl]-
- 4880-04-02-Propenoicacid, 2-methyl-, pentamethyldisiloxanyl ester (9CI)
- 4880-88-0Eburnamenin-14(15H)-one,(3a,16a)-
- 488-10-8Jasmone
- 488-11-92-Butenoicacid, 2,3-dibromo-4-oxo-, (2Z)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Mesitaldehyde |
EINECS | 207-662-1 |
| CAS No. | 487-68-3 | Density | 1.988 g/cm3 |
| PSA | 17.07000 | LogP | 2.42430 |
| Solubility | N/A | Melting Point |
10-12 °C(lit.) |
| Formula | C10H12O | Boiling Point | 241.5 °C at 760 mmHg |
| Molecular Weight | 148.205 | Flash Point | 105.6 °C |
| Transport Information | N/A | Appearance | Light Yellow Liquid |
| Safety | 26-36-24/25 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
2,4,6-Trimethylbenzaldehyde;2-Mesitylenecarboxaldehyde;Mesitylaldehyde;Mesitylenecarboxaldehyde;NSC 29094; |
Article Data | 140 |
Mesitaldehyde Synthetic route
| Conditions | Yield |
|---|---|
| With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; iodic acid In N,N-dimethyl-formamide at 20℃; for 2h; Reagent/catalyst; Temperature; Inert atmosphere; | 99% |
| With 5-nitro-3-oxo-1λ3-benzo[d][1,2]iodaoxol-1(3H)-yl acetate In N,N-dimethyl-formamide at 60℃; for 24h; Reagent/catalyst; | 98% |
| With N-Bromosuccinimide; β‐cyclodextrin In methanol; water; acetone at 20℃; for 8h; | 96% |
| Conditions | Yield |
|---|---|
| With 1-dodecyl-3-methylimidazolium iron chloride; periodic acid at 30℃; for 1.5h; | 98% |
| With 4Na(1+)*6H(1+)*NiMo6O24(10-)=Na4H6NiMo6O24; oxygen In water; acetonitrile at 20℃; under 760.051 Torr; for 12h; Irradiation; | 91% |
| With sodium nitrate; acetic acid In water for 8h; Reflux; | 83% |
| With potassium hydroxide; cetyltrimethylammonim bromide; potassium nitrate In water for 7.5h; pH=10 - 11; Reflux; | 82% |
| With (NH4)4[ZnMo6O18(OH)6]; oxygen In water; acetonitrile at 60℃; under 760.051 Torr; for 12h; | 81% |
| Conditions | Yield |
|---|---|
| Stage #1: 1,3,5-trimethyl-benzene With titanium tetrachloride In dichloromethane at 0℃; for 1h; Inert atmosphere; Stage #2: Dichloromethyl methyl ether In dichloromethane at 0℃; for 0.75h; Inert atmosphere; regioselective reaction; | 96% |
| With silver trifluoromethanesulfonate In dichloromethane at -78℃; for 0.333333h; Inert atmosphere; | 69% |
| With dichloromethane; titanium tetrachloride |
- 40188-34-9
2,4,6-trimethylbenzaldehyde oxime
- 487-68-3
mesytaldehyde
| Conditions | Yield |
|---|---|
| With chromium trioxide-kieselghur reagent In dichloromethane for 3h; Reflux; | 92% |
| With 2-iodoxybenzoic acid; β‐cyclodextrin In water; acetone at 20℃; for 12h; | 90% |
| With iodobenzene; β‐cyclodextrin; potassium bromide In water; acetone at 20℃; for 12h; | 90% |
| Conditions | Yield |
|---|---|
| Stage #1: N,N-dimethyl-formamide With trichlorophosphate In dichloromethane at -10℃; for 0.333333h; Stage #2: 1,3,5-trimethyl-benzene In dichloromethane at -5℃; for 6.16667h; Solvent; Reflux; | 90.3% |
- 487-68-3
mesytaldehyde
| Conditions | Yield |
|---|---|
| With water at 20℃; | 89% |
| Conditions | Yield |
|---|---|
| With sodium periodate In N,N-dimethyl-formamide at 150℃; for 0.833333h; | 87% |
| With sodium periodate; N,N-dimethyl-formamide at 150℃; for 0.833333h; | 87% |
| With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 65℃; for 2.5h; | 80% |
| With potassium hydroxide; 2-nitropropane In isopropyl alcohol at 40 - 45℃; for 0.333333h; | 75% |
| With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 60℃; |
- 487-68-3
mesytaldehyde
| Conditions | Yield |
|---|---|
| With Bromoform; potassium tert-butylate In hexane at -78℃; for 3h; | 87% |
| Multi-step reaction with 2 steps 1: chloroform; water / 24 h / 20 °C 2: air / 20 °C View Scheme |
- 4885-02-3
Dichloromethyl methyl ether
- 108-67-8
1,3,5-trimethyl-benzene
A
- 487-68-3
mesytaldehyde
B
- 4126-83-4
1-(dichloromethyl)-2,4,6-trimethylbenzene
C
- 134284-55-2
3-dichloromethyl-2,4,6-trimethylbenzaldehyde
D
- 134284-56-3
1,3-bis(dichloromethyl)mesitylene
| Conditions | Yield |
|---|---|
| With titanium tetrachloride In dichloromethane at 20 - 25℃; for 0.25h; Further byproducts given; | A 84% B 3 % Chromat. C 3 % Chromat. D 1 % Chromat. |
| With titanium tetrachloride In dichloromethane for 0.25h; Ambient temperature; Yields of byproduct given; | A 84% B n/a C n/a D n/a |
| With aluminium trichloride In dichloromethane at 20 - 25℃; for 0.25h; Further byproducts given; | A 55 % Chromat. B 10% C 10 % Chromat. D 25 % Chromat. |
| Conditions | Yield |
|---|---|
| With C25H19(1+)*BF4(1-) In dichloromethane at 20℃; for 3.5h; Reagent/catalyst; Schlenk technique; Inert atmosphere; | A 79% B 65% |
Mesitaldehyde Consensus Reports
Mesitaldehyde Specification
The IUPAC name of Mesityl aldehyde is 2,4,6-trimethylbenzaldehyde. With the CAS registry number 487-68-3, it is also named as 2-Mesitylenecarboxaldehyde; Benzaldehyde, 2,4,6-trimethyl-. The product's categories are aromatic aldehydes & derivatives (substituted), benzaldehyde and aromatics. It is light yellow liquid which is soluble in benzene and toluene. It is sensitive to air. So it should be stored in a tightly closed container which is placed in a cool, dry, well-ventilated area away from incompatible substances.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 3.02; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.02; (4)ACD/LogD (pH 7.4): 3.02; (5)#H bond acceptors: 1; (6)#H bond donors: 0; (7)#Freely Rotating Bonds: 1; (8)Index of Refraction: 1.546; (9)Molar Refractivity: 47.48 cm3; (10)Molar Volume: 149.9 cm3; (11)Polarizability: 18.82×10-24 cm3; (12)Surface Tension: 35.2 dyne/cm; (13)Enthalpy of Vaporization: 47.85 kJ/mol; (14)Vapour Pressure: 0.0357 mmHg at 25°C; (15)Rotatable Bond Count: 1; (16)Tautomer Count: 4; (17)Exact Mass: 148.088815; (18)MonoIsotopic Mass: 148.088815; (19)Topological Polar Surface Area: 17.1; (20)Heavy Atom Count: 11.
Preparation of Mesityl aldehyde: It can be obtained by 2,4,6-trimethyl-benzoyl chloride. This reaction needs reagent palladium-barium sulfate and xylene by Hydrogenation.
.gif)
Uses of Mesityl aldehyde: It can be used in organic synthesis, and also can be used as medicine and other fine chemical products. It can reacts with 2,3-dihydro-furan to get endo-7-(2,4,6-Trimethylphenyl)-2,6-dioxabicyclo[3.2.0]heptan. This reaction needs reagent K2CO3 and solvent benzene at temperature of 6-8 °C and irradiation. The reaction time is 8.5 hours. The yield is 97%.
.gif)
When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. So people should avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing.
People can use the following data to convert to the molecule structure.
1. SMILES: O=Cc1c(C)cc(C)cc1C;
2. InChI: InChI=1/C10H12O/c1-7-4-8(2)10(6-11)9(3)5-7/h4-6H,1-3H3.
What can I do for you?
Get Best Price
