Cyclopropaneaceticacid,1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-

 
IUPAC Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
Molecular Formula: C₃₅H₃₆ClNO₃S
Molecular Weight: 586.18 g/mol
Classification Code: Anti-asthmatic agents; Hormone Antagonists; Hormones, Hormone Substitutes, and Hormone Antagonists; Leukotriene antagonists; Respiratory System Agents
Index of Refraction: 1.677
Molar Refractivity: 173.71 cm³
Molar Volume: 460.7 cm³
Surface Tension: 59.7 dyne/cm
Density: 1.272 g/cm³
Flash Point: 407.7 °C
Enthalpy of Vaporization: 114.78 kJ/mol
Boiling Point: 750.5 °C at 760 mmHg
Vapour Pressure of Montelukast (CAS NO.158966-92-8): 1.17E-23 mmHg at 25 °C

  Montelukast (CAS NO.158966-92-8) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is usually administered orally. Montelukast is a CysLT1 antagonist; that is it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene, and results in less inflammation.

  Montelukast (CAS NO.158966-92-8), its Synonyms are (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ; 1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ; Cyclopropaneacetic acid, 1-((((1R)-1-(3-((1E)-2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)- ; Cyclopropaneacetic acid, 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-, (R-(E))- .