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Analytical Methods:
For occupational chemical analysis use OSHA: #27 or NIOSH: Nitrosamines, 2522.
Empirical Formula: C5H10N2O
Molecular Weight: 114.1457 g/mol
EINECS: 202-886-6
Index of Refraction: 1.55
Density: 1.17 g/cm3
Flash Point: 92.8 °C
Enthalpy of Vaporization: 44.75 kJ/mol
Boiling Point: 229.8 °C at 760 mmHg
Vapour Pressure: 0.103 mmHg at 25 °C
Storage tempreture: 2-8 °C
Stable: Stable. Combustible. Incompatible with strong oxidizing agents.
Structure of N-Nitrosopiperidine (CAS NO.100-75-4):
IUPAC Name: 1-Nitrosopiperidine
Product Categories: Nitrosamine;Alpha Sort;Cancer Research;Carcinogens;Volatiles/ Semivolatiles
1. | trn-dmg-orl 425 ppm | ENMUDM Environmental Mutagenesis. 7 (1985),349. | ||
2. | sce-hmn:lym 10 mmol/L | TCMUE9 Topics in Chemical Mutagenesis. 1 (1984),129. | ||
3. | scu-ham TDLo:100 mg/kg (14D preg):NEO,TER | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 90 (1977),71. | ||
4. | orl-rat LD50:200 mg/kg | ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103. | ||
5. | scu-rat LD50:100 mg/kg | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 80 (1973),17. | ||
6. | ivn-rat LD50:60 mg/kg | ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103. | ||
7. | orl-ham LD50:617 mg/kg | CALEDQ Cancer Letters (Shannon, Ireland). 21 (1983),219. | ||
8. | scu-ham LD50:324 mg/kg | ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 81 (1974),251. |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 287.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 287.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 28 ,1982,p. 151.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Hazard Codes of N-Nitrosopiperidine (CAS NO.100-75-4): T,F
Risk Statements: 25-40-39/23/24/25-23/24/25-11
R11:Highly flammable.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R25 :Toxic if swallowed.
R39:Danger of very serious irreversible effects.
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 53-23-26-36/37/39-45-36/37-16-9
S9:Keep container in a well-ventilated place.
S16:Keep away from sources of ignition.
S23:Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53:Avoid exposure - obtain special instructions before use.
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
For occupational chemical analysis use OSHA: #27 or NIOSH: Nitrosamines, 2522.
N-Nitrosopiperidine ,its cas register number is 100-75-4. It also can be called Piperidine, 1-nitroso- ; Nitrosopiperidine ;and 1-nitrosopiperidine . It may react with strong oxidizing agents, especially peroxyacids.