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PROSTAGLANDIN A1

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Name

PROSTAGLANDIN A1

EINECS 234-237-8
CAS No. 14152-28-4 Density 1.086g/cm3
PSA 74.60000 LogP 4.28030
Solubility Melting Point 41 - 43 C
Formula C20H32 O4 Boiling Point 510.7°Cat760mmHg
Molecular Weight 336.472 Flash Point 276.7°C
Transport Information HAZARD Appearance white to yellow crystalline solid
Safety Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also other prostaglandins. Risk Codes N/A
Molecular Structure Molecular Structure of 14152-28-4 (PROSTAGLANDIN A1) Hazard Symbols UN NO.
Synonyms

3-Cyclopentene-1-heptanoicacid, 2-(3-hydroxy-1-octenyl)-5-oxo- (8CI); 15-Hydroxy-9-oxoprosta-10,13-dienoicacid; 15a-Hydroxy-9-ketoprosta-10,13-dienoicacid; 15a-Hydroxy-9-oxo-10,13E-prostadienoicacid; PGA1; Prostaglandin A1; Prostaglandin E1-217

 

PROSTAGLANDIN A1 Chemical Properties

Prostaglandin A1 ,abbreviated form:PGA1
MF: C20H32O4
MW: 336.47
EINECS: 234-237-8
Solubility in acetone: 10 mg/mL, clear
PROSTAGLANDIN A1(PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

PROSTAGLANDIN A1 Uses

Prostaglandin A1 has been shown to decrease blood pressure and improve kidney function in pregnant women with severe hypertension. The ability of prostaglandin A1 to prevent the aggregation of platelets (clumping of cells involved in blood clotting) may also be beneficial.
In addition, according to a Research about  assessed the effectiveness of prostaglandin A1 and dihydralazine in managing severe preeclampsia as detected in 20 women during early labor,prostaglandin A1 has an oxytocic effect (ability to cause uterine contraction), and can induce or enhance labor.

PROSTAGLANDIN A1 Toxicity Data With Reference

1.   

oms-hmn:oth 2500 μg/L

   CNREA8    Cancer Research. 43 (1983),513.

RTECS  GY5977900

PROSTAGLANDIN A1 Safety Profile

Safety Information about PROSTAGLANDIN A1:
Safety Statements  22-24/25
WGK Germany  3 

Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
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