Pyrocatechol

Base Information

• Chemical Name: Pyrocatechol
• CAS No.: 4055-72-5
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Hs Code.: 2909500000
• Mol file: 4055-72-5.mol

Synonyms:2-hydroxy-3-methoxy-5-(2-propenyl)-phenol;5-allyl-3-methoxy-pyrocatechol;1,2-Benzenediol,3-methoxy-5-(2-propenyl);5-hydroxyeugenol;3-methoxy-5-allyl-1,2-benzenediol;

Chemical Property of Pyrocatechol

Chemical Property:

• PSA: 49.69000
• LogP: 1.83490

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Allyl-1-methoxy-2,3-dihydroxybenzene is an intermediate in the synthesis of Myristicin (M884600), a naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells.

Technology Process of Pyrocatechol

There total 14 articles about Pyrocatechol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-allyloxy-3-methoxy-phenol (71186-63-5) → 5-Hydroxyeugenol (4055-72-5)

Guidance literature:

at 150 ℃; for 336000h;

DOI:10.1002/jccs.200100011

Reference yield:

5-allyl-2-hydroxy-3-methoxybenzaldehyde (22934-51-6) → 5-Hydroxyeugenol (4055-72-5)

Guidance literature:

With alkaline aqueous H₂O₂;

Reference yield:

5-hydroxyconiferyl 9-acetate → 5-Hydroxyeugenol (4055-72-5)

Guidance literature:

With propenylphenol synthase from Larrea tridentata; NADH; In aq. buffer; at 30 ℃; pH=6.5; Kinetics;

DOI:10.1016/j.abb.2013.10.019

upstream raw materials:

5-allyl-2-hydroxy-3-methoxybenzaldehyde

2-allyloxy-3-methoxy-phenol

2-(allyloxy)-6-methoxyphenol

Shashenoside II

Downstream raw materials:

myristicin

5-hydroxyconiferyl aldehyde

(E)-3-methoxy-5-(3-oxoprop-1-en-1-yl)-1,2-phenylene diacetate

(E)-3-(3,4-dihydroxy-5-methoxyphenyl)acrylaldehyde

Refernces

• 1、 Kim, Sung-Jin,Vassao, Daniel G.,Moinuddin, Syed G.A.,Bedgar, Diana L.,Davin, Laurence B.,Lewis, Norman G.. "Allyl/propenyl phenol synthases from the creosote bush and engineering production of specialty/commodity chemicals, eugenol/isoeugenol, in Escherichia coli". . p. 37 - 46. Retrieved 2014/01/06.
• 2、 Mamouni,Soukri,Lazar,Akssira,Guillaumet. "Synthesis of 2H-1,5-benzodioxepin and 2,5-dihydro-1,6-benzodioxocin derivatives via ring-closing metathesis reaction". . p. 2631 - 2633. Retrieved 2007/10/03.