Myristicin

Base Information

• Chemical Name: Myristicin
• CAS No.: 607-91-0
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Hs Code.: 2932999099
• European Community (EC) Number: 210-146-9
• UNII: 04PD6CT78W
• DSSTox Substance ID: DTXSID1025693
• Nikkaji Number: J36.670F
• Wikipedia: Myristicin
• Wikidata: Q414057
• Metabolomics Workbench ID: 47098
• ChEMBL ID: CHEMBL481044
• Mol file: 607-91-0.mol

Synonyms:5-allyl-1-methoxy-2,3-(methylenedioxy)benzene;asaricin;myristicin

Chemical Property of Myristicin

Chemical Property:

• Vapor Pressure: 0.0105mmHg at 25°C
• Melting Point: <-20oC
• Refractive Index: 1.524
• Boiling Point: 276.5 °C at 760 mmHg
• Flash Point: 89.8 °C
• PSA: 27.69000
• Density: 1.137 g/cm³
• LogP: 2.15240
• Storage Temp.: 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 192.078644241
• Heavy Atom Count: 14
• Complexity: 205

Purity/Quality:

98%,99%, ^*data from raw suppliers

Myristicin ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R52/53:
• Hazard Codes: R52/53:
• Statements: 52/53
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Plant Toxins
• Canonical SMILES: COC1=CC(=CC2=C1OCO2)CC=C
• Description: Myristicin is an alkenylbenzene present in small amounts in the essential oil of nutmeg that is reported to act as a serotonin receptor antagonist, a weak monamine oxidase inhibitor, and to produce hallucinogenic effects. Abuse of myristicin has led to fatal poisoning, which has prompted improved methods for HPLC determination of myristicin in human plasma. This product is intended for forensic and research purposes.
• Uses: A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells

Technology Process of Myristicin

There total 8 articles about Myristicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Hydroxyeugenol (4055-72-5) + 1,1-dibromomethane (74-95-3) → myristicin (607-91-0)

Guidance literature:

With potassium carbonate;

DOI:10.1039/jr9490000436 DOI:10.1021/ja01189a016

Reference yield:

2-allyloxy-3-methoxy-phenol (71186-63-5) → myristicin (607-91-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 170 - 200 °C / unter Wasserstoff

2: potassium carbonate

With potassium carbonate;

DOI:10.1039/jr9490000436 DOI:10.1021/ja01189a016

Reference yield:

2-(allyloxy)-6-methoxyphenol (51066-05-8) → myristicin (607-91-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 170 - 200 °C / unter Wasserstoff

2: potassium carbonate

With potassium carbonate;

DOI:10.1039/jr9490000436 DOI:10.1021/ja01189a016

upstream raw materials:

diiodomethane

5-Hydroxyeugenol

1,1-dibromomethane

acetone

Downstream raw materials:

trans-isomyristicin

Refernces

• 1、 Fujita,Yamashita. "-". . p. 3553. Retrieved 1973.
• 2、 -. "Method of causing the reduction of physiological and/or subjective reactivity to stress in humans being subjected to stress conditions". . . Retrieved 2008/06/13.