2,4-Diphenylpyrrole

Base Information

• Chemical Name: 2,4-Diphenylpyrrole
• CAS No.: 3274-56-4
• Molecular Formula: C16H13 N
• Molecular Weight: 219.286
• Hs Code.: 2933990090
• Mol file: 3274-56-4.mol

Synonyms:Pyrrole,2,4-diphenyl- (7CI,8CI); 2,4-Diphenyl-1H-pyrrole; 2,4-Diphenylpyrrole; NSC116650

Chemical Property of 2,4-Diphenylpyrrole

Chemical Property:

• Vapor Pressure: 9.27E-07mmHg at 25°C
• Melting Point: 179-180 °C(Solv: benzene (71-43-2))
• Boiling Point: 416.4°Cat760mmHg
• PKA: 16.70±0.50(Predicted)
• Flash Point: 175.1°C
• PSA: 15.79000
• Density: 1.105g/cm³
• LogP: 4.34870
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2,4-Diphenylpyrrole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Diphenylpyrrole

There total 63 articles about 2,4-Diphenylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitro-1,3-diphenyl-butan-1-one (6277-67-4) → 2,4-diphenylpyrrole (3274-56-4)

Guidance literature:

With morpholine; sulfur; ammonium acetate; In neat (no solvent); at 80 ℃; for 0.5h; Reagent/catalyst; Solvent; Temperature;

DOI:10.1055/s-0035-1561852

Reference yield: 96.0%

carbon monoxide (201230-82-2) + 1,3-diphenylprop-2-ynyl-1-amine (134166-47-5) → 2,4-diphenylpyrrole (3274-56-4)

Guidance literature:

With hydrogen; triphenylphosphine; dirhodium tetraacetate; at 70 ℃; for 20h; under 20685.9 Torr;

DOI:10.1016/S0040-4039(00)74496-0

Reference yield: 90.0%

(Z)-3-[(prop-2-yn-1-yl)amino]-1,3-diphenyl-prop-2-en-1-one → 2,4-diphenylpyrrole (3274-56-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 24h;

upstream raw materials:

3,5-diphenyl-3,4-dihydro-2H-pyrrole

(3,5-diphenyl-1H-pyrrol-2-yl)(3,5-diphenylpyrrol-2-ylidene)amine

(3-chloromethyl-3-phenyloxiranyl)phenylmethanone

(E)-4-bromo-2,3-epoxy-1,3-diphenyl-1-butanone

Downstream raw materials:

3-(3,5-diphenyl-pyrrol-2-ylidene)-5-phenyl-3H-[1,2,4]dithiazole

3,5-diphenyl-2-((E)-5-phenyl-[1,2]dithiol-3-ylidene)-2H-pyrrole

1,3,5,7-tetraphenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene

3,5-diphenyl-1H-pyrrole-2-carbaldehyde

Refernces

• 1、 Trofimov,Tarasova,Shmidt,Mikkaleva,Sinegovskaya. "Unexpected transformations of O-vinylacetophenone oxime in the system ButOK - THF". . p. 594 - 596. Retrieved 1997.
• 2、 -. "Preparation method of 2,4-di-substituted pyrrole derivative". Paragraph 0020; 0021; 0022; 0023. . Retrieved 2018/07/30.
• 3、 Zhang, Xinxin,Zheng, Songlin,Zhang, Songlin. "Ytterbium-mediated synthesis of 2,4-diarylpyrroles from α-bromo oxime ethers". . p. 54254 - 54257. Retrieved 2017/12/05.