(E)-3,3'-Dimethoxystilbene

Base Information

• Chemical Name: (E)-3,3'-Dimethoxystilbene
• CAS No.: 6325-63-9
• Molecular Formula: C16H16 O2
• Molecular Weight: 240.302
• NSC Number: 30994
• Nikkaji Number: J1.019.140H,J336.355D
• Mol file: 6325-63-9.mol

Synonyms:NSC30994;6325-63-9;SCHEMBL700055;SCHEMBL700056;ZBFPZUMLGZJSNN-MDZDMXLPSA-;NSC-30994;InChI=1/C16H16O2/c1-17-15-7-3-5-13(11-15)9-10-14-6-4-8-16(12-14)18-2/h3-12H,1-2H3/b10-9+

Chemical Property of (E)-3,3'-Dimethoxystilbene

Chemical Property:

• Boiling Point: 372.7°Cat760mmHg
• Flash Point: 148.4°C
• Density: 1.089g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 240.115029749
• Heavy Atom Count: 18
• Complexity: 236

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C=CC2=CC(=CC=C2)OC
• Isomeric SMILES: COC1=CC=CC(=C1)/C=C/C2=CC(=CC=C2)OC

Technology Process of (E)-3,3'-Dimethoxystilbene

There total 45 articles about (E)-3,3'-Dimethoxystilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3-methoxybenzyl)triphenylphosphonium bromide (72311-12-7) → 1,2-bis(3-methoxyphenyl)ethylene (6325-63-9)

Guidance literature:

With sodium hydride; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1021/ol061594z

Reference yield: 98.0%

3-methoxystyrene (626-20-0) → (E)-3,3'-dimethoxystilbene (6325-63-9,20657-34-5,84385-62-6)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; Reflux;

DOI:10.1021/ja3002666

Reference yield: 96.0%

m-methoxybenzyl chloride (824-98-6) → (E)-3,3'-dimethoxystilbene (6325-63-9,20657-34-5,84385-62-6)

Guidance literature:

With triethyl borate; sodium hydride; triphenylphosphine; In 1,4-dioxane; at 100 ℃; for 12h; Inert atmosphere;

upstream raw materials:

3-methoxybenzaldehyde azine

acetic acid

(Z)-4-methyl-2-pentene

cyclohexane

Downstream raw materials:

3,3'-dimethoxybenzil

1,2-bis(3-methoxyphenyl)ethane

3,3'-(3,3-dibromocyclopropane-1,2-diyl)bis(methoxybenzene)

(R,R)-(+)-1,2-bis(3-methoxyphenyl)ethane-1,2-diol

Refernces

• 1、 -. "Efficient preparation method of symmetric diarylethene compound". Paragraph 0059-0061. . Retrieved 2021/02/10.
• 2、 Wang, Shun,Lokesh, Nanjundappa,Hioe, Johnny,Gschwind, Ruth M.,K?nig, Burkhard. "Photoinitiated carbonyl-metathesis: Deoxygenative reductive olefination of aromatic aldehydes: Via photoredox catalysis". . p. 4580 - 4587. Retrieved 2019/05/14.