2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane

Base Information

• Chemical Name: 2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane
• CAS No.: 428-92-2
• Molecular Formula: C3H3 Cl2 F3 O
• Molecular Weight: 182.957
• Hs Code.: 2909199090
• European Community (EC) Number: 207-053-0
• DSSTox Substance ID: DTXSID50962705
• Nikkaji Number: J122.146I
• Mol file: 428-92-2.mol

Synonyms:2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane;428-92-2;EINECS 207-053-0;C3H3Cl2F3O;C3-H3-Cl2-F3-O;DTXSID50962705;2-Chloro-1,1,2-trifluoroethyl chloromethyl ether;Chloromethyl 2-chloro-1,1,2-trifluoroethyl ether;(2-chloro-1,1,2-trifluoro-ethoxy)-chloro-methane;Ether, chloromethyl 2-chloro-1,1,2-trifluoroethyl;Ethane, 2-chloro-1-(chloromethoxy)-1,1,2-trifluoro-

Chemical Property of 2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane

Chemical Property:

• Vapor Pressure: 18.1mmHg at 25°C
• Boiling Point: 120.7°Cat760mmHg
• Flash Point: 26.8°C
• PSA: 9.23000
• Density: 1.476g/cm³
• LogP: 2.32650
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 181.9513046
• Heavy Atom Count: 9
• Complexity: 89.1

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(OC(C(F)Cl)(F)F)Cl

Technology Process of 2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane

There total 3 articles about 2-Chloro-1-(chloromethoxy)-1,1,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-1,1,2-trifluoroethyl methyl ether (425-87-6) → 2-chloro-1,1,2-trifluoroethyl chloromethyl ether (428-92-2)

Guidance literature:

Photochlorierung in fluessiger Phase;

DOI:10.1021/ja01634a073 DOI:10.1021/ja01123a048

Reference yield:

2-chloro-1,1,2-trifluoroethyl methyl ether (425-87-6) → 2-chloro-1,1,2-trifluoroethyl chloromethyl ether (428-92-2) + (2-chloro-1,1,2-trifluoroethyl)dichloromethylether (428-96-6) + (2-chloro-1,1,2-trifluoroethyl)trichloromethylether (460-99-1) + dichloromethyl(2,2-dichloro-1,1,2-trifluoroethyl)ether (29771-98-0)

Guidance literature:

With chlorine; Irradiation;

DOI:10.1135/cccc19930565

Reference yield:

→ 2-chloro-1,1,2-trifluoroethyl chloromethyl ether (428-92-2)

Guidance literature:

CH3O-CF2-CHFCl, Cl2;

upstream raw materials:

2-chloro-1,1,2-trifluoroethyl methyl ether

Refernces

• 1、 Terrell,Speers,Szur,Treadwell,Ucciardi. "General anesthetics. 1. Halogenated methyl ethyl ethers as anesthetic agents.". . p. 517 - 519. Retrieved 2007/10/12.