1-Bromo-2-(2-bromoethyl)benzene

Base Information

• Chemical Name: 1-Bromo-2-(2-bromoethyl)benzene
• CAS No.: 1074-15-3
• Molecular Formula: C8H8 Br2
• Molecular Weight: 263.96
• Hs Code.: 2903999090
• European Community (EC) Number: 833-513-0
• NSC Number: 338402
• DSSTox Substance ID: DTXSID40910311
• Nikkaji Number: J455.485J
• Wikidata: Q72452063
• Mol file: 1074-15-3.mol

Synonyms:1-bromo-2-(2-bromoethyl)benzene;1074-15-3;1-BROMO-2-(2-BROMOETHYL)-BENZENE;2-(o-bromophenyl)ethyl bromide;NSC338402;o-bromophenethyl bromide;2-Bromophenethyl bromide;beta-bromoethyl bromobenzene;SCHEMBL216488;beta-bromo ethyl bromo benzene;DTXSID40910311;1-(2-bromoethyl)-2-bromobenzene;BAA07415;MFCD00027929;AKOS014197347;NSC-338402;SS-4837;CS-0156656;FT-0762897;EN300-212272;A801692;J-504381

Chemical Property of 1-Bromo-2-(2-bromoethyl)benzene

Chemical Property:

• Vapor Pressure: 0.0167mmHg at 25°C
• Boiling Point: 263.5°Cat760mmHg
• Flash Point: 126.4°C
• PSA: 0.00000
• Density: 1.74g/cm³
• LogP: 3.38650
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 263.89723
• Heavy Atom Count: 10
• Complexity: 93.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-bromo-2-(2-bromoethyl)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CCBr)Br

Technology Process of 1-Bromo-2-(2-bromoethyl)benzene

There total 10 articles about 1-Bromo-2-(2-bromoethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-bromophenylethyl alcohol (1074-16-4) → 1-bromo-2-(2-bromoethyl)benzene (1074-15-3)

Guidance literature:

With phosphorus tribromide; at 100 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.1c02283

Reference yield: 89.0%

2-bromostyrene (2039-88-5) → 1-bromo-2-(2-bromoethyl)benzene (1074-15-3)

Guidance literature:

With hydrogen bromide; acetic acid; In hexane; at 0 ℃; for 2h;

DOI:10.1039/c6ob00692b

Reference yield:

2-(2'bromophenyl)-1-iodoethane (113163-19-2) → 1-bromo-2-(2-bromoethyl)benzene (1074-15-3) + ethylbenzene (100-41-4,27536-89-6) + 1-bromo-2-ethylbenzene (1973-22-4) + 2-phenethyl iodide (17376-04-4) + 2-bromostyrene (2039-88-5) + 1-phenyl-2-bromoethane (103-63-9)

Guidance literature:

With methanol; tert.-butyl lithium; In tetrahydrofuran; at -98 ℃; Product distribution; Mechanism;

DOI:10.1021/ja00160a053

upstream raw materials:

benzocyclobutene

2-bromophenylethyl alcohol

phenylacetic acid

2-(2'bromophenyl)-1-iodoethane

Downstream raw materials:

1,1-diphenyl-2,3-dihydro-1H-benzo[b]silole

7-(2'-bromophenyl)-5,5-bis(ethoxycarbonyl)-1,2-heptadiene

1,1-bis(ethoxycarbonyl)-3-(2'-bromophenyl)propane

2-<2-(o-bromophenyl)ethyl>-2-(trimethylsilyl)-1,3-dithiane

Refernces

• 1、 Ishida, Naoki,Okumura, Shintaro,Murakami, Masahiro. "Site- and regio-selective incorporation of carbon dioxide into the C(sp2)Si bond of benzosilacyclobutenes". . p. 570 - 572. Retrieved 2018.
• 2、 Chen, Xing,Li, Mengke,Liu, Zhipeng,Yang, Can,Xie, Haisheng,Hu, Xinwei,Su, Shi-Jian,Jiang, Huanfeng,Zeng, Wei. "Bimetal Cooperatively Catalyzed Arylalkynylation of Alkynylsilanes". supporting information. p. 6724 - 6728. Retrieved 2021/09/08.
• 3、 -. "COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS". Paragraph 001156; 001157; 001158; 001159. . Retrieved 2019/01/10.