6-Methyl-2,3,4,9-tetrahydro-1H-carbazole

Base Information

• Chemical Name: 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole
• CAS No.: 17177-17-2
• Molecular Formula: C13H15 N
• Molecular Weight: 185.269
• Hs Code.: 2933990090
• European Community (EC) Number: 634-118-4
• NSC Number: 103143
• DSSTox Substance ID: DTXSID60295596
• Nikkaji Number: J307.697K
• Wikidata: Q82035607
• Mol file: 17177-17-2.mol

Synonyms:6-Methyl-2,3,4,9-tetrahydro-1H-carbazole;17177-17-2;NSC103143;Maybridge1_006329;SCHEMBL2515756;HMS559H15;DTXSID60295596;BMBRPEXJJPILQP-UHFFFAOYSA-N;MFCD00086178;STK347603;AKOS000295381;NSC-103143;1,2,3,4-Tetrahydro-6-methylcarbazole;6-methyl-1,2,3,4-tetrahydrocarbazole;NCGC00320595-01;RH 00819;FT-0691065;EN300-230808;F79772;AB01314980-02;F1443-1085

Chemical Property of 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole

Chemical Property:

• Vapor Pressure: 0.00017mmHg at 25°C
• Boiling Point: 340.4°C at 760 mmHg
• Flash Point: 148.3°C
• PSA: 15.79000
• Density: 1.122g/cm³
• LogP: 3.35510
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 185.120449483
• Heavy Atom Count: 14
• Complexity: 213

Purity/Quality:

98%min ^*data from raw suppliers

6-METHYL-1,2,3,4-TETRAHYDROCARBAZOLE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)NC3=C2CCCC3

Technology Process of 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole

There total 1 articles about 6-Methyl-2,3,4,9-tetrahydro-1H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 4-Methylazobenzol (949-87-1) → 1,2,3,4-tetrahydrocarbazole (942-01-8) + 6-methyl-2,3,4,9-tetrahydro-1H-carbazole (17177-17-2)

Guidance literature:

With 4,4'-bipyridine; 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane; In benzene-d6; at 100 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1021/acs.joc.0c02661

Reference yield: 95.0%

6-methyl-2,3,4,9-tetrahydro-1H-carbazole (17177-17-2) → 3-Methyl-9H-carbazole (4630-20-0)

Guidance literature:

palladium on activated charcoal; In various solvent(s); for 5.5h; Heating;

Reference yield: 62.12%

benzoyl chloride (98-88-4) + 6-methyl-2,3,4,9-tetrahydro-1H-carbazole (17177-17-2) → (6-methyl-1,2,3,4-tetrahydro-9H-carbazol-9-yl) (phenyl) methanone

Guidance literature:

With sodium hydroxide; In water; for 0.166667h;

DOI:10.2174/1570180814666170602084037

upstream raw materials:

cyclohexanone

4-Methylazobenzol

Downstream raw materials:

3-Methyl-9H-carbazole

6-methyl-1,2,3,4,4a,9a-hexahydro-carbazole

4-hydroxy-2-methyl-5-phenyl-8,9,10,11-tetrahydropyrido[3,2,1-jk]carbazol-6-one

C₂₂H₂₆N₂O

Refernces