3-Methyl-9H-carbazole

Base Information

• Chemical Name: 3-Methyl-9H-carbazole
• CAS No.: 4630-20-0
• Molecular Formula: C13H11N
• Molecular Weight: 181.237
• Hs Code.: 2933990090
• European Community (EC) Number: 225-048-1
• NSC Number: 10154
• UNII: 18UX66Z45K
• DSSTox Substance ID: DTXSID90196805
• Nikkaji Number: J46.570D
• Wikidata: Q63398622
• Metabolomics Workbench ID: 122686
• ChEMBL ID: CHEMBL1173768
• Mol file: 4630-20-0.mol

Synonyms:3-methylcarbazole

Chemical Property of 3-Methyl-9H-carbazole

Chemical Property:

• Vapor Pressure: 2.59E-05mmHg at 25°C
• Melting Point: 265℃
• Refractive Index: 1.736
• Boiling Point: 369.1 °C at 760 mmHg
• Flash Point: 165.4 °C
• PSA: 15.79000
• Density: 1.19 g/cm³
• LogP: 3.62950
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 181.089149355
• Heavy Atom Count: 14
• Complexity: 213

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Methyl-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)NC3=CC=CC=C32

Technology Process of 3-Methyl-9H-carbazole

There total 134 articles about 3-Methyl-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-methyl-2,3,4,9-tetrahydro-1H-carbazole (6933-54-6,100986-21-8) → 3-Methyl-9H-carbazole (4630-20-0)

Guidance literature:

With copper(II) choride dihydrate; In dimethyl sulfoxide; at 100 ℃; for 7h; Time; Solvent; Catalytic behavior;

DOI:10.1016/j.tetlet.2018.01.061

Reference yield: 95.0%

6-methyl-2,3,4,9-tetrahydro-1H-carbazole (17177-17-2) → 3-Methyl-9H-carbazole (4630-20-0)

Guidance literature:

palladium on activated charcoal; In various solvent(s); for 5.5h; Heating;

Reference yield: 87.0%

C20H21N3O2S (1451422-86-8) → 3-Methyl-9H-carbazole (4630-20-0)

Guidance literature:

C₂₀H₂₁N₃O₂S; With magnesium sulfate heptahydrate; In methanol; dichloromethane;

With sodium tetrahydroborate; palladium 10% on activated carbon; at 100 ℃; for 0.0833333h; under 1551.49 - 2585.81 Torr; Microwave irradiation;

DOI:10.1002/jhet.999

upstream raw materials:

3-methyl-2,3,4,9-tetrahydro-1H-carbazole

1-(4-methylphenyl)-1H-benzo[d][1,2,3]triazole

5-methyl-1-phenyl-1H-1,2,3-benzotriazole

1-p-toluidino-cyclopentanecarboxylic acid

Downstream raw materials:

3,9-dimethyl-9H-carbazole

8-formyl-3-methylcarbazole

6-formyl-3-methylcarbazole

1-formyl-3-methylcarbazole

Refernces

• 1、 Mukherjee, M.,Mukherjee, S.,Shaw, A. K.,Ganguly, S. N.. "MUKONICINE, A CARBAZOLE ALKALOID FROM LEAVES OF MURRAYA KOENIGII". . p. 2328 - 2329. Retrieved 1983.
• 2、 Mukherjee, S.,Mukherjee, M.,Ganguly, S. N.. "GLYCOZOLININE, A CARBAZOLE DERIVATIVE FROM GLYCOSMIS PENTAPHYLLA". . p. 1064 - 1065. Retrieved 1983.
• 3、 Akiyama, Toshiki,Arisawa, Mitsuhiro,Haneoka, Hitoshi,Harada, Kazuo,Hasegawa, Jun-Ya,Honma, Tetsuo,Mashima, Kazushi,Sato, Yoshihiro,Shimoda, Shuhei,Shio, Yasunori,Suzuki, Takeyuki,Tamenori, Yusuke,Tsurugi, Hayato,Tsuruta, Kazuki,Wada, Yuki,Yamada, Makito. "Self-Assembled Multilayer Iron(0) Nanoparticle Catalyst for Ligand-Free Carbon-Carbon/Carbon-Nitrogen Bond-Forming Reactions". . p. 7244 - 7249. Retrieved 2020/10/12.
• 4、 Kawauchi, Daichi,Noda, Kenta,Komatsu, Yoshiyuki,Yoshida, Kei,Ueda, Hirofumi,Tokuyama, Hidetoshi. "Aerobic Dehydrogenation of N-Heterocycles with Grubbs Catalyst: Its Application to Assisted-Tandem Catalysis to Construct N-Containing Fused Heteroarenes". . p. 15793 - 15798. Retrieved 2020/10/12.