Acetic acid, 2,2,2-trifluoro-, 1-Methylpropyl ester

Base Information

• Chemical Name: Acetic acid, 2,2,2-trifluoro-, 1-Methylpropyl ester
• CAS No.: 1536-78-3
• Molecular Formula: C6H9 F3 O2
• Molecular Weight: 170.131
• Mol file: 1536-78-3.mol

Synonyms:Aceticacid, trifluoro-, 1-methylpropyl ester (9CI); Acetic acid, trifluoro-,sec-butyl ester (6CI,7CI,8CI); (?à)-2-Butyl trifluoroacetate; 2-Trifluoroacetoxybutane; NSC 55883; sec-Butyltrifluoroacetate

Chemical Property of Acetic acid, 2,2,2-trifluoro-, 1-Methylpropyl ester

Chemical Property:

• Vapor Pressure: 33.5mmHg at 25°C
• Boiling Point: 102.5°Cat760mmHg
• Flash Point: °C
• PSA: 26.30000
• Density: 1.15g/cm³
• LogP: 1.89040

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid, 2,2,2-trifluoro-, 1-Methylpropyl ester

There total 5 articles about Acetic acid, 2,2,2-trifluoro-, 1-Methylpropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon monoxide (201230-82-2) + trifluoroacetic acid (76-05-1) + n-butane (106-97-8,9003-29-6,9021-92-5) → formic acid (64-18-6) + trifluoroacetic acid-methyl ester (431-47-0) + ethyl trifluoroacetate, (383-63-1) + 1-(trifluoroacetoxy)propane (383-66-4) + n-butyl trifluoroacetate (367-64-6) + 2-butyl trifluoroacetate (1536-78-3) + acetic acid (64-19-7,77671-22-8) + butanone (78-93-3)

Guidance literature:

With rhodium(III) chloride; oxygen; copper(II) trifluoroacetate; sodium chloride; In water; at 80 ℃; under 45004.5 Torr; Autoclave; Inert atmosphere;

DOI:10.1134/S0023158410050071

Reference yield:

trifluoroacetic acid (76-05-1) + n-butane (106-97-8,9003-29-6,9021-92-5) → formic acid (64-18-6) + trifluoroacetic acid-methyl ester (431-47-0) + ethyl trifluoroacetate, (383-63-1) + 1-(trifluoroacetoxy)propane (383-66-4) + n-butyl trifluoroacetate (367-64-6) + 2-butyl trifluoroacetate (1536-78-3) + acetic acid (64-19-7,77671-22-8) + butanone (78-93-3)

Guidance literature:

With carbon monoxide; rhodium(III) trichloride hydrate; water; oxygen; sodium chloride; copper(II) oxide; at 80 ℃; for 2h; Inert atmosphere; Autoclave;

DOI:10.1134/S0965544110050026

Reference yield:

(R)-sec-butyl 4-methylbenzenesulfonate (61530-30-1) + trifluoroacetic acid (76-05-1) → 1-butylene (106-98-9,9003-28-5) + trans-2-Butene (624-64-6) + 2-butyl trifluoroacetate (1536-78-3)

Guidance literature:

With sodium 2,2,2-trifluoroacetate; at 25 ℃; Rate constant; Mechanism; Product distribution; var. amounts of reagent, optical stability;

DOI:10.1021/jo00172a017

upstream raw materials:

diethyl ether

trifluoroacetic anhydride

iso-butanol

(R)-sec-butyl 4-methylbenzenesulfonate

Downstream raw materials:

N-butyl-2,2,2-trifluoroacetamide

Refernces

• 1、 Chepaikin,Bezruchenko,Menchikova,Moiseeva,Gekhman. "Catalytic oxidation of hydrocarbons of natural and oil gas". experimental part. p. 332 - 337. Retrieved 2011/04/26.
• 2、 Allen, Annette D.,Ambidge, Christopher,Tidwell, Thomas T.. "Stereochemistry of Trifluoroacetolysis of Optically Active 2-Butyl Tosylate. A Test for Hydrogen Bridging". . p. 4527 - 4530. Retrieved 2007/10/02.