Quinolin-8-ol hydrochloride

Base Information

• Chemical Name: Quinolin-8-ol hydrochloride
• CAS No.: 16862-11-6
• Molecular Formula: C9H8ClNO
• Molecular Weight: 181.622
• Hs Code.: 2933499090
• European Community (EC) Number: 240-884-7
• DSSTox Substance ID: DTXSID70937511
• ChEMBL ID: CHEMBL3251402
• Mol file: 16862-11-6.mol

Synonyms:Quinolin-8-ol hydrochloride;16862-11-6;quinolin-8-ol hydrochloride(1:1);quinolin-8-ol;hydrochloride;8-HYDROXYQUINOLINE HYDROCHLORIDE;Quinolin-8-ol HCl;8-Hydroxy Quinoline HCl;EINECS 240-884-7;8-Quinolinol, hydrochloride;C9H7NO.ClH;8-Quinolinol hydrochloride;SCHEMBL599825;CHEMBL3251402;8-Hydroxyquinoline, hydrochloride;DTXSID70937511;Quinolin-8-ol--hydrogen chloride (1/1)

Chemical Property of Quinolin-8-ol hydrochloride

Chemical Property:

• Appearance/Colour: Yellow crystal powder
• Vapor Pressure: 0.00508mmHg at 25°C
• Melting Point: 179-184 °C
• Boiling Point: 267 °C at 760 mmHg
• Flash Point: 143.1 °C
• PSA: 33.12000
• LogP: 2.74240
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 181.0294416
• Heavy Atom Count: 12
• Complexity: 138

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-HYDROXYQUINOLINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)O)N=CC=C2.Cl

Technology Process of Quinolin-8-ol hydrochloride

There total 3 articles about Quinolin-8-ol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-quinolinol (148-24-3,24804-14-6) → 8-Hydroxyquinoline hydrochloride (16862-11-6)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1039/C6RA21684F

Reference yield:

thorium(IV) chloride * 6 (8-quinolinol) → tris(8-quinolinolato)thorium(IV) chloride (21308-09-8) + 8-Hydroxyquinoline hydrochloride (16862-11-6)

Guidance literature:

DOI:10.1039/J19680002273

Reference yield:

8-quinolinol (148-24-3,24804-14-6) + thorium tetrachloride (10026-08-1) → tetrakis(8-quinolinolato)thorium(IV) (18153-67-8) + 8-Hydroxyquinoline hydrochloride (16862-11-6)

Guidance literature:

molar ratio of educts 1:8, heating at 200°C, or at 140°C in a sealed tube for 3 h; sublimation of C9H7NO*HCl at 250°C and 0.05 Torr, sublimation of product at ca. 350°C and 0.05 Torr;

DOI:10.1039/J19680002273

upstream raw materials:

8-quinolinol

thorium tetrachloride

Downstream raw materials:

8-Chinolin-N-methylcarbamat

5-Chloro-8-hydroxyquinoline

Refernces

• 1、 Marathe,Gite, V.V.. "Encapsulation of 8-HQ as a corrosion inhibitor in PF and UF shells for enhanced anticorrosive properties of renewable source based smart PU coatings". . p. 114436 - 114446. Retrieved 2016.