POLYOXYETHYLENE 10 LAURYL ETHER

Base Information

• Chemical Name: POLYOXYETHYLENE 10 LAURYL ETHER
• CAS No.: 6540-99-4
• Molecular Formula: C32H66O11
• Molecular Weight: 626.869
• Hs Code.: 2909499000
• Mol file: 6540-99-4.mol

Synonyms:SINOPOL 1110;Ethoxylated C12-14 alcohols;Laureth-10;Polyethylene glycol 500 lauryl ether;PEG-10 Lauryl ether;

Chemical Property of POLYOXYETHYLENE 10 LAURYL ETHER

Chemical Property:

• Vapor Pressure: 2.29E-19mmHg at 25°C
• Refractive Index: 1.46
• Boiling Point: 645.126 °C at 760 mmHg
• Flash Point: 343.96 °C
• PSA: 112.53000
• Density: 1.015 g/cm³
• LogP: 4.06560

Purity/Quality:

99%, ^*data from raw suppliers

Decaethylene glycol mono-dodecyl ether nonionic surfactant ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of POLYOXYETHYLENE 10 LAURYL ETHER

There total 9 articles about POLYOXYETHYLENE 10 LAURYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

heptaethylene glycol monododecyl ether (3055-97-8) + C6H12O6S → decaethylene glycol monodecyl ether (6540-99-4)

Guidance literature:

heptaethylene glycol monododecyl ether; With sodium hydride; In tetrahydrofuran; mineral oil; for 0.5h; Inert atmosphere;

C₆H₁₂O₆S; In tetrahydrofuran; mineral oil; pH=2; Inert atmosphere;

With sulfuric acid; In tetrahydrofuran; water; mineral oil; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.molpharmaceut.7b00496

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → decaethylene glycol monodecyl ether (6540-99-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine; dmap; thionyl chloride / dichloromethane / 0 - 25 °C

2.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / Inert atmosphere

2.2: pH 2 / Inert atmosphere

2.3: 2 h / 80 °C / Inert atmosphere

With dmap; thionyl chloride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1021/acs.molpharmaceut.7b00496

Reference yield:

Tetraethylene glycol (112-60-7) → decaethylene glycol monodecyl ether (6540-99-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: triethylamine; dmap; thionyl chloride / dichloromethane / 0 - 25 °C

2.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / Inert atmosphere

2.2: pH 2 / Inert atmosphere

2.3: 2 h / 80 °C / Inert atmosphere

3.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / Inert atmosphere

3.2: pH 2 / Inert atmosphere

3.3: 2 h / 80 °C / Inert atmosphere

4.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / Inert atmosphere

4.2: pH 2 / Inert atmosphere

4.3: 2 h / 80 °C / Inert atmosphere

With dmap; thionyl chloride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1021/acs.molpharmaceut.7b00496

upstream raw materials:

pentaethylene glycol

1-(2-{2-[2-(2-chloro-ethoxy)-ethoxy]-ethoxy}-ethoxy)-dodecane

oxirane

1-dodecyl alcohol

Refernces

• 1、 -. "Nonionic surfactant having reduced toxicity and environmental hormone activity and preperation method of the same". Paragraph 0161-0163. . Retrieved 2017/06/13.