Methanol, (trimethylsilyl)-, carbamate

Base Information

• Chemical Name: Methanol, (trimethylsilyl)-, carbamate
• CAS No.: 3124-45-6
• Molecular Formula: C₅H₁₃NO₂Si
• Molecular Weight: 147.249
• NSC Number: 96783
• DSSTox Substance ID: DTXSID80185167
• Wikidata: Q83056153
• Mol file: 3124-45-6.mol

Synonyms:3124-45-6;Methanol, (trimethylsilyl)-, carbamate;(Trimethylsilyl)methanol carbamate;Carbamic acid, (trimethylsilyl)methyl ester;BRN 2410278;(Trimethylsilyl)methyl ester of carbamic acid;DTXSID80185167;NSC96783;NSC 96783;NSC-96783;AKOS006363872

Chemical Property of Methanol, (trimethylsilyl)-, carbamate

Chemical Property:

• Vapor Pressure: 0.0528mmHg at 25°C
• Boiling Point: 234.5°Cat760mmHg
• Flash Point: 95.6°C
• Density: 0.956g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 147.071555192
• Heavy Atom Count: 9
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)COC(=O)N

Technology Process of Methanol, (trimethylsilyl)-, carbamate

There total 2 articles about Methanol, (trimethylsilyl)-, carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

isocyanate de chlorosulfonyle (1189-71-5) + (trimethylsilyl)methanol (3219-63-4) → Carbaminsaeure-trimethylsilylmethylester (3124-45-6)

Guidance literature:

isocyanate de chlorosulfonyle; (trimethylsilyl)methanol; In acetonitrile; at 0 - 20 ℃; for 1.08333h; Inert atmosphere;

With water; In acetonitrile; at 0 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/acs.inorgchem.6b00602

Reference yield:

(trimethylsilyl)methanol (3219-63-4) + phenyl chloroformate (1885-14-9) → Carbaminsaeure-trimethylsilylmethylester (3124-45-6)

Guidance literature:

Multistep reaction; (i) Py, (ii) liq. NH₃;

DOI:10.1021/jm00329a012

upstream raw materials:

(trimethylsilyl)methanol

phenyl chloroformate

isocyanate de chlorosulfonyle

Refernces

• 1、 Fessenden,Coon. "Silicon-substituted medicinal agents. Silacarbamates related to meprobamate.". . p. 604 - 608. Retrieved 2007/10/05.