2,2-DIFLUOROETHYL ACETATE

Base Information

• Chemical Name: 2,2-DIFLUOROETHYL ACETATE
• CAS No.: 1550-44-3
• Molecular Formula: C4H6F2O2
• Molecular Weight: 124.087
• Hs Code.: 2915390090
• Mol file: 1550-44-3.mol

Synonyms:Ethanol,2,2-difluoro-, acetate (6CI,8CI,9CI);Acetic acid 2,2-difluoroethyl ester;

Chemical Property of 2,2-DIFLUOROETHYL ACETATE

Chemical Property:

• Vapor Pressure: 322.306mmHg at 25°C
• Refractive Index: 1.352
• Boiling Point: 71.5 °C at 760 mmHg
• Flash Point: 22°C
• PSA: 26.30000
• Density: 1.135 g/cm³
• LogP: 0.81460

Purity/Quality:

99% ^*data from raw suppliers

2,2-Difluoroethyl Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 10-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-DIFLUOROETHYL ACETATE

There total 8 articles about 2,2-DIFLUOROETHYL ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 2,2-difluoroethyl acetate (1550-44-3)

Guidance literature:

Reference yield: 99.23%

difluoromethyl alcohol (1426-06-8) + acetyl chloride (75-36-5) → 2,2-difluoroethyl acetate (1550-44-3)

Guidance literature:

With triethylamine; In dichloromethane; at 5 ℃; for 3h; Temperature; Reagent/catalyst;

Reference yield: 99.0%

1-chloro-2,2-difluoroethane (338-65-8) + potassium acetate (127-08-2) → 2,2-difluoroethyl acetate (1550-44-3)

Guidance literature:

In dimethyl sulfoxide; at 120 ℃; for 4.5h; Solvent; Temperature;

upstream raw materials:

acetyl chloride

2-bromo-1,1-difluoroethane

sodium acetate

1-chloro-2,2-difluoroethane

Downstream raw materials:

difluoroethanol

Refernces

• 1、 -. "Method for synthesizing 2,2-difluoroethanol from R142". Paragraph 0029-0031; 0035-0037. . Retrieved 2020/05/02.
• 2、 -. "Difluoroethanol synthesis method using 2,2-difluoro-1-chloroethane as raw material". Paragraph 0019; 0022; 0025; 0028; 0031. . Retrieved 2018/06/26.