H-Lys(Tos)-Oh

Base Information

• Chemical Name: H-Lys(Tos)-Oh
• CAS No.: 2130-76-9
• Molecular Formula: C13H20N2O4S
• Molecular Weight: 300.379
• Hs Code.: 29309099
• NSC Number: 164908,66203
• ChEMBL ID: CHEMBL1988193
• Mol file: 2130-76-9.mol

Synonyms:NSC66203;SCHEMBL3730989;2-amino-6-[(4-methylphenyl)sulfonylamino]hexanoic acid;CHEMBL1988193;NSC-66203;NSC164908;AKOS025243651;NSC-164908;NCI60_021523;(2S)-2-azaniumyl-6-[(4-methylphenyl)sulfonylamino]hexanoate

Chemical Property of H-Lys(Tos)-Oh

Chemical Property:

• Vapor Pressure: 4.67E-11mmHg at 25°C
• Melting Point: 231-234 °C
• Refractive Index: 1.56
• Boiling Point: 505.9 °C at 760 mmHg
• Flash Point: 259.8 °C
• PSA: 117.87000
• Density: 1.264 g/cm³
• LogP: 3.02750
• Storage Temp.: −20°C
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 300.11437830
• Heavy Atom Count: 20
• Complexity: 397

Purity/Quality:

98.5% ^*data from raw suppliers

H-Lys(Tos)-Oh ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NCCCCC(C(=O)O)N

Technology Process of H-Lys(Tos)-Oh

There total 3 articles about H-Lys(Tos)-Oh which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

Copper(II); (S)-2-amino-6-(toluene-4-sulfonylamino)-hexanoate → (S)-2-amino-6-(4-methylphenylsulfonamido)hexanoic acid (2130-76-9)

Guidance literature:

With sodium sulfide; In water; at 25 - 30 ℃; for 0.166667h;

DOI:10.1016/j.tetlet.2006.05.069

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → (S)-2-amino-6-(4-methylphenylsulfonamido)hexanoic acid (2130-76-9)

Guidance literature:

DOI:10.1021/ja01603a047 DOI:10.1021/ja01521a036

Reference yield:

→ (S)-2-amino-6-(4-methylphenylsulfonamido)hexanoic acid (2130-76-9)

Guidance literature:

entspr. Kupfer-Komplex, Aethylendiamin-tetraessigsaeure;

DOI:10.1246/bcsj.38.676

upstream raw materials:

p-toluenesulfonyl chloride

Downstream raw materials:

α-Formyl-ε-p-toluolsulfonyl-L-lysin

(S)-2-(Carboxymethyl-amino)-6-(toluene-4-sulfonylamino)-hexanoic acid

N^α-Methyl-N^α-benzyl-N^ε-tosyl-L-lysin

Nαand-Methyl-Nεand-tosyl-L-lysin

Refernces