N,N-DIALLYL-4-METHYLBENZENESULFONAMIDE

Base Information

• Chemical Name: N,N-DIALLYL-4-METHYLBENZENESULFONAMIDE
• CAS No.: 50487-72-4
• Molecular Formula: C13H17NO2S
• Molecular Weight: 251.349
• Hs Code.: 2935009090
• Mol file: 50487-72-4.mol

Synonyms:N-allyl-N-but-3-enyl-4-methyl-benzenesulfonamide;diallyl N-tosylamide;N,N-Diallyl-4-methylbenzenesulfonamide;N,N-diallyl-4-toluenesulfonamide;HMS1703N04;

Chemical Property of N,N-DIALLYL-4-METHYLBENZENESULFONAMIDE

Chemical Property:

• Vapor Pressure: 2.5E-05mmHg at 25°C
• Boiling Point: 358.7°Cat760mmHg
• PKA: -6.18±0.70(Predicted)
• Flash Point: 170.7°C
• PSA: 45.76000
• Density: 1.104g/cm³
• LogP: 3.43850
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99.9% ^*data from raw suppliers

N,N-Diallyl-4-methylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-DIALLYL-4-METHYLBENZENESULFONAMIDE

There total 18 articles about N,N-DIALLYL-4-METHYLBENZENESULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methyl-N,N-diprop-2-ynylbenzenesulfonamide (18773-54-1) → N,N-Diallyltosylamide (50487-72-4)

Guidance literature:

With formic acid; nickel dibromide; zinc; In tetrahydrofuran; at 80 ℃; for 16h; Sealed tube;

DOI:10.1021/acs.joc.5b01047

Reference yield: 97.0%

toluene-4-sulfonamide (70-55-3) + allyl alcohol (107-18-6) → N,N-Diallyltosylamide (50487-72-4)

Guidance literature:

With Ni{α,α'-bis(diphenylphosphino)-o-xylene}2; In neat (no solvent); at 80 ℃; for 18h; Schlenk technique; Inert atmosphere; Green chemistry;

DOI:10.1002/ejoc.201600500

Reference yield: 96.0%

p-toluenesulfonyl chloride (98-59-9) + diallylamine (124-02-7) → N,N-Diallyltosylamide (50487-72-4)

Guidance literature:

diallylamine; With triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

p-toluenesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja406169s

upstream raw materials:

p-toluenesulfonyl chloride

diallylamine

Allyl ether

toluene-4-sulfonamide

Downstream raw materials:

(3R,4R)-3-Dimethoxymethyl-4-methyl-1-(toluene-4-sulfonyl)-pyrrolidine

(3R,4S)-3-Dimethoxymethyl-4-methyl-1-(toluene-4-sulfonyl)-pyrrolidine

1-[(4-methylphenyl)sulfonyl]-2,5-dihydro-1H-pyrrole

3-methyl-4-methylene-2-(4-tolylsulfonyl)pyrrolidine

Refernces

• 1、 Gou, Shaohua,Yin, Ting,Liu, Kun,Guo, Qipeng. "Water-soluble complexes of an acrylamide copolymer and ionic liquids for inhibiting shale hydration". . p. 2155 - 2161. Retrieved 2015.
• 2、 Chen, Weiqiang,Li, Hui-Jing,Liu, Ying,Nan, Xiang,Wu, Yan-Chao,Zhang, Yin-Lin. "Synthesis of N -Sulfonyl- and N -Acylpyrroles via a Ring-Closing Metathesis/Dehydrogenation Tandem Reaction". supporting information. p. 3651 - 3666. Retrieved 2019/09/30.
• 3、 Azizi, Mohamed Salah,Edder, Youssef,Karim, Abdallah,Sauthier, Mathieu. "Nickel(0)-Catalyzed N-Allylation of Amides and p-Toluenesulfonamide with Allylic Alcohols under Neat and Neutral Conditions". . p. 3796 - 3803. Retrieved 2016/08/16.