Trityl 2-(tritylamino)acetate

Base Information

• Chemical Name: Trityl 2-(tritylamino)acetate
• CAS No.: 6662-92-6
• Molecular Formula: C40H33NO2
• Molecular Weight: 234.382
• DSSTox Substance ID: DTXSID00412149
• Wikidata: Q82219374
• Mol file: 6662-92-6.mol

Synonyms:6662-92-6;Trityl 2-(tritylamino)acetate;trityl (tritylamino)acetate;DTXSID00412149;AKOS024430231

Chemical Property of Trityl 2-(tritylamino)acetate

Chemical Property:

• Vapor Pressure: 7.96E-18mmHg at 25°C
• Boiling Point: 670.2°Cat760mmHg
• Flash Point: 359.1°C
• Density: 1.16g/cm³
• XLogP3: 9.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 11
• Exact Mass: 559.251129295
• Heavy Atom Count: 43
• Complexity: 726

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCC(=O)OC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Technology Process of Trityl 2-(tritylamino)acetate

There total 9 articles about Trityl 2-(tritylamino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-phenyl-2-decanone (32508-91-1) → 1-phenyldecan-2-ol (6662-92-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; water; for 15h; Ambient temperature;

Reference yield:

iodobenzene (591-50-4) + C18H34B(1-)*Li(1+) → 1-phenyldecan-2-ol (6662-92-6)

Guidance literature:

iodobenzene; C₁₈H₃₄B^(1-)*Li⁽¹⁺⁾; With [2,2]bipyridinyl; bis(acetylacetonate)nickel(II); In tetrahydrofuran; at 60 ℃; for 12h; Inert atmosphere; Sealed tube; Glovebox;

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 3h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201706719

Reference yield:

oct-1-ene (111-66-0,25068-25-1) → 1-phenyldecan-2-ol (6662-92-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 3 h / 0 - 20 °C / Glovebox; Inert atmosphere

1.2: 0.08 h / 0 - 20 °C / Glovebox; Inert atmosphere

2.1: [2,2]bipyridinyl; bis(acetylacetonate)nickel(II) / tetrahydrofuran / 12 h / 60 °C / Inert atmosphere; Sealed tube; Glovebox

2.2: 3 h / 0 - 20 °C / Inert atmosphere; Sealed tube

With [2,2]bipyridinyl; bis(acetylacetonate)nickel(II); In tetrahydrofuran;

DOI:10.1002/anie.201706719

upstream raw materials:

1-phenyl-2-decanone

phenylacetaldehyde

1-dodecylbromide

1-Bromoheptane

Downstream raw materials:

nonan-1-al

Refernces

• 1、 Takikawa, Mami,Uno, Kiyoko,Ooi, Takashi,Kusumi, Takenori,Akera, Shusaku,Muramatsu, Morimitsu,Mega, Hirohiko,Horita, Chie. "Crenulacetal C, a marine diterpene, and its synthetic mimics inhibiting Polydora websterii, a harmful lugworm damaging pearl cultivation". . p. 462 - 466. Retrieved 2007/10/03.
• 2、 Shankaran, R.,Talekar, D. G.,Rao, A. S.. "SYNTHESIS OF ALDEHYDES AND BENZYLKETONES THROUGH FRAGMENTATION OF HOMOBENZYLIC ALCOHOLS". . p. 141 - 150. Retrieved 2007/10/02.