N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide

Base Information

• Chemical Name: N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide
• CAS No.: 5842-34-2
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.241
• DSSTox Substance ID: DTXSID70362228
• Wikidata: Q82145105
• Mol file: 5842-34-2.mol

Synonyms:N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide;5842-34-2;STK319994;N-(3-{[2-(3,4-dimethylphenoxy)acetyl]amino}phenyl)butanamide;Cambridge id 5842342;Oprea1_261195;DTXSID70362228;AKOS000453659;AP-970/12435490;SR-01000221609;SR-01000221609-1;N-(3-{[(3,4-dimethylphenoxy)acetyl]amino}phenyl)butanamide

Chemical Property of N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide

Chemical Property:

• Vapor Pressure: 4.46E-15mmHg at 25°C
• Boiling Point: 615.4°Cat760mmHg
• Flash Point: 326°C
• Density: 1.175g/cm³
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 340.17869263
• Heavy Atom Count: 25
• Complexity: 441

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(=O)NC1=CC(=CC=C1)NC(=O)COC2=CC(=C(C=C2)C)C

Technology Process of N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide

There total 12 articles about N-[3-[[2-(3,4-dimethylphenoxy)acetyl]amino]phenyl]butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenol (108-95-2,27073-41-2) → (+/-)-2,2-dimethyl-3t-phenoxy-cyclopropane-r-carboxylic acid (5842-34-2,5863-14-9,15231-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone

2: KOtBu, tBuOH

3: (i) Cu, (ii) KOH, MeOH

With potassium tert-butylate; potassium carbonate; tert-butyl alcohol; In acetone;

Reference yield:

phenol (108-95-2,27073-41-2) → (+/-)-2,2-dimethyl-3c-phenoxy-cyclopropane-r-carboxylic acid (5842-34-2,5863-14-9,15231-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone

2: KOtBu, tBuOH

3: (i) Cu, (ii) KOH, MeOH

With potassium tert-butylate; potassium carbonate; tert-butyl alcohol; In acetone;

Reference yield:

2-methyl-1-phenoxy-2-propanol (13524-74-8) → (+/-)-2,2-dimethyl-3t-phenoxy-cyclopropane-r-carboxylic acid (5842-34-2,5863-14-9,15231-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂, Py

2: KOH

3: (i) Cu, (ii) KOH, MeOH

With pyridine; potassium hydroxide; thionyl chloride;

upstream raw materials:

ethyl 2,2-dimethyl-3-phenoxycyclopropane-1-carboxylate

diazoacetic acid ethyl ester

((2-methylprop-1-en-1-yl)oxy)benzene

2-methyl-1-phenoxy-2-propanol