DEHYDROABIETINE

Base Information

• Chemical Name: DEHYDROABIETINE
• CAS No.: 5323-56-8
• Molecular Formula: C19H28
• Molecular Weight: 256.431
• Hs Code.: 2902909090
• Mol file: 5323-56-8.mol

Synonyms:Phenanthrene,1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethyl- (8CI); Dehydroabietin;NSC 2782; Nordehydroabietane

Chemical Property of DEHYDROABIETINE

Chemical Property:

• Vapor Pressure: 0.000175mmHg at 25°C
• Boiling Point: 339.9 °C at 760 mmHg
• Flash Point: 157.8 °C
• PSA: 0.00000
• Density: 0.939 g/cm³
• LogP: 5.45010

Purity/Quality:

99% ^*data from raw suppliers

DEHYDROABIETINE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DEHYDROABIETINE

There total 13 articles about DEHYDROABIETINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenyl dehydroselenoabietate (76932-72-4) → 18-Norabieta-8,11,13-triene (5323-56-8,19407-17-1,19407-18-2,32298-75-2,32367-41-2)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃;

DOI:10.1002/hlca.19800630823

Reference yield: 65.0%

dehydroabietic acid (1740-19-8) → 18-Norabieta-8,11,13-triene (5323-56-8,19407-17-1,19407-18-2,32298-75-2,32367-41-2)

Guidance literature:

With nickel(II) perchlorate hexahydrate; phenylsilane; 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; In tetrahydrofuran; N,N-dimethyl-formamide; isopropyl alcohol; at 40 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201609662

Reference yield:

13-isopropyl-15.15-diphenyl-podocarpatrien-(C)-ol-(15) (53084-92-7) → benzophenone (119-61-9) + 1,4a-dimethyl-7-(methylethyl)-1,2,3,4,9,10,10a,4a-octahydrophenanthrene (5323-56-8)

Guidance literature:

(+)-1.4a-dimethyl-7-isopropyl-1.2.3.4.4a.9.10.10a-octahydro-phenanthrene from 18.18-diphenyl-abietatrien-(8.11.13)-ol-(18); Destillation unter vermindertem Druck;

DOI:10.1021/ja01145a542 DOI:10.1021/jo01143a018 DOI:10.1002/hlca.19500330642 DOI:10.1021/ja01194a043

upstream raw materials:

13-isopropyl-15.15-diphenyl-podocarpatrien-(C)-ol-⁽¹⁵⁾

1-(3-isopropyl-phenethyl)-2,6-dimethyl-cyclohexanol

sulfuric acid

2,6-dimethylcyclohexanone

Downstream raw materials:

Retene

Refernces

• 1、 Qin, Tian,Malins, Lara R.,Edwards, Jacob T.,Merchant, Rohan R.,Novak, Alexander J. E.,Zhong, Jacob Z.,Mills, Riley B.,Yan, Ming,Yuan, Changxia,Eastgate, Martin D.,Baran, Phil S.. "Nickel-Catalyzed Barton Decarboxylation and Giese Reactions: A Practical Take on Classic Transforms". supporting information. p. 260 - 265. Retrieved 2016/12/30.