Pentanoic acid, 3-ethyl-3-[[(4-methylphenyl)methyl]thio]-

Base Information

• Chemical Name: Pentanoic acid, 3-ethyl-3-[[(4-methylphenyl)methyl]thio]-
• CAS No.: 104532-41-4
• Molecular Formula: C₁₅H₂₂O₂S
• Molecular Weight: 266.404
• Mol file: 104532-41-4.mol

Synonyms:

Chemical Property of Pentanoic acid, 3-ethyl-3-[[(4-methylphenyl)methyl]thio]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pentanoic acid, 3-ethyl-3-[[(4-methylphenyl)methyl]thio]-

There total 5 articles about Pentanoic acid, 3-ethyl-3-[[(4-methylphenyl)methyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pentan-3-one (96-22-0) → β,β-diethyl-S-(4-methylbenzyl)-β-mercaptopropionic acid (104532-41-4)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH / toluene

2: piperidine / Heating

3: 1.) 5percent K₂CO₃, 2.) H₃PO₄ / 1.) MeOH, H₂O, THF

With piperidine; phosphoric acid; sodium hydride; potassium carbonate; In toluene;

DOI:10.1021/jm00162a001

Reference yield:

ethyl 3-ethylpent-2-enoate (15249-93-1) → β,β-diethyl-S-(4-methylbenzyl)-β-mercaptopropionic acid (104532-41-4)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine / Heating

2: 1.) 5percent K₂CO₃, 2.) H₃PO₄ / 1.) MeOH, H₂O, THF

With piperidine; phosphoric acid; potassium carbonate;

DOI:10.1021/jm00162a001

Reference yield:

3-Ethyl-3-(4-methyl-benzylsulfanyl)-pentanoic acid ethyl ester (109212-79-5) → β,β-diethyl-S-(4-methylbenzyl)-β-mercaptopropionic acid (104532-41-4)

Guidance literature:

With phosphoric acid; potassium carbonate; Multistep reaction; 1.) MeOH, H₂O, THF;

DOI:10.1021/jm00162a001

upstream raw materials:

3-ethyl-2-pentenoic acid

4-methylbenzylthiol

3-Ethyl-3-(4-methyl-benzylsulfanyl)-pentanoic acid ethyl ester

ethyl 3-ethylpent-2-enoate

Refernces