Lysylglutamic acid

Base Information

• Chemical Name: Lysylglutamic acid
• CAS No.: 45234-02-4
• Molecular Formula: C11H21N3O5
• Molecular Weight: 275.305
• Hs Code.: 2924199090
• UNII: H34V7IM5ML
• DSSTox Substance ID: DTXSID50196442
• Nikkaji Number: J89.512A
• Wikidata: Q27144733
• Metabolomics Workbench ID: 78882
• ChEMBL ID: CHEMBL365790
• Mol file: 45234-02-4.mol

Synonyms:AB-0 peptide;AB-17;H-Lys(H-Glu-OH)-OH;Lys-Glu;lysylglutamic acid;normophthal;Vilon

Chemical Property of Lysylglutamic acid

Chemical Property:

• Melting Point: 195-197 °C
• Boiling Point: 596.4 °C at 760 mmHg
• PKA: 3.00±0.10(Predicted)
• Flash Point: 314.5 °C
• PSA: 155.74000
• Density: 1.29 g/cm³
• LogP: 0.66840
• Storage Temp.: -15°C
• XLogP3: -6.3
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 10
• Exact Mass: 275.14812078
• Heavy Atom Count: 19
• Complexity: 322

Purity/Quality:

99%min ^*data from raw suppliers

N-L-Lysyl-L-glutamic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCN)CC(C(=O)NC(CCC(=O)O)C(=O)O)N
• Isomeric SMILES: C(CCN)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N

Technology Process of Lysylglutamic acid

There total 1 articles about Lysylglutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → LysGluGlu (157535-07-4) + lysine tetrapeptide (997-20-6) + poly(L-lysine), 5-mer (19431-21-1) + Lys-Glu (45234-02-4) + L-glutamyl-L-glutamic acid (3929-61-1) + Lys-Lys-Lys (13184-14-0) + C11H19N3O4 (473452-81-2) + C16H24N4O6 + C22H36N6O7 + C27H41N7O9 + C28H48N8O8 + C32H46N8O11 + C33H53N9O10 + C34H60N10O9 + C33H55N9O11 + C38H58N10O12 + C38H58N10O12 + C39H65N11O11 + C44H70N12O13 + C49H75N13O15 + C55H87N15O16 + C50H82N14O14 + C49H75N13O15 + C44H70N12O13 + C39H65N11O11 + C38H58N10O12 + C38H58N10O12 + C33H53N9O10 + C32H46N8O11 + C27H41N7O9 + C21H29N5O8 + C16H24N4O6 + C11H19N3O4 + C55H87N15O16 + C54H80N14O17 + C49H75N13O15 + C44H70N12O13 + C39H65N11O11 + C38H58N10O12 + C38H58N10O12 + C35H67N11O8 + C33H53N9O10 + C33H55N9O11 + C28H48N8O8 + C32H46N8O11 + C27H41N7O9 + C22H36N6O7 + C17H31N5O5 + C50H82N14O14 + C40H72N12O10 + C44H70N12O13 + C39H65N11O11 + C34H60N10O9 + C29H55N9O7 + C23H43N7O6 + C36H44N8O14 + C31H39N7O12 + C26H34N6O10 + C21H29N5O8 + C20H24N4O10 + C15H19N3O8 + C10H14N2O6 (757898-70-7) + C39H69N11O13 + C33H57N9O12 + C32H50N8O13 + C32H48N8O12 + C27H45N7O11 + C28H50N8O9 + C27H43N7O10 + C22H38N6O8 + C17H33N5O6 (175175-64-1) + C17H33N5O6 (175176-04-2) + C34H62N10O10 + C39H67N11O12 + C40H74N12O11 + C45H79N13O13 + C46H86N14O12 + C45H81N13O14 + C33H57N9O12 + C38H62N10O14 + C43H67N11O16 + C44H74N12O15 + EKKK + EKKE (92172-18-4) + EKEE + KEKKK + EKKEK + EKEEK + KEKKKK (532436-32-1) + EKKEKK (927893-91-2) + EKEEKE (927894-29-9) + glu-Lys (5891-52-1,5891-53-2,130004-26-1)

Guidance literature:

With sulfuric acid; at 140 ℃; for 300h; Time; Temperature;

DOI:10.1007/s11172-012-0060-3

Reference yield:

D-glucose (50-99-7) + Lys-Glu (45234-02-4) → 1,4-pyrazine (290-37-9) + 2-Methylpyrazine (109-08-0) + 2,5-dimethyl-pyrazine (123-32-0) + 2,3-dimethylpyrazine (5910-89-4) + 2-ethyl-3,6-dimethylpyrazine (13360-65-1) + 2,6-dimethylpyrazine (108-50-9) + 2,3,5-trimethylpyrazine (14667-55-1) + 2-ethyl-3,5-dimethylpyrazine (13925-07-0) + 2-ethyl-5-methypyrazine (13360-64-0) + 5-ethyl-2,3-dimethylpyrazine (15707-34-3)

Guidance literature:

In water; at 130 ℃; for 2h; pH=8;

DOI:10.1021/jf903898t

Reference yield:

Lys-Glu (45234-02-4) + 2-oxopropanal (78-98-8) → 2-Methylpyrazine (109-08-0) + 2,5-dimethyl-pyrazine (123-32-0) + 2,3-dimethylpyrazine (5910-89-4) + 2-ethyl-3,6-dimethylpyrazine (13360-65-1) + 2,6-dimethylpyrazine (108-50-9) + 2,3,5-trimethylpyrazine (14667-55-1) + 3-ethenyl-2,5-dimethylpyrazine (80935-98-4) + 1-(5-methylpyrazin-2-yl)ethanone (22047-27-4) + 5-ethyl-2,3-dimethylpyrazine (15707-34-3) + 2,5-dimethyl-3-propylpyrazine (18433-97-1)

Guidance literature:

In water; at 130 ℃; for 2h; pH=8;

DOI:10.1021/jf903898t

upstream raw materials:

L-glutamic acid

L-Lysine hydrochloride

Downstream raw materials:

1,4-pyrazine

2-Methylpyrazine

2,5-dimethyl-pyrazine

2,3-dimethylpyrazine

Refernces