1-Naphthyl phosphate

Base Information

• Chemical Name: 1-Naphthyl phosphate
• CAS No.: 1136-89-6
• Molecular Formula: C10H9O4P
• Molecular Weight: 224.153
• Hs Code.: 2919900090
• European Community (EC) Number: 214-502-4
• DSSTox Substance ID: DTXSID10862858
• Nikkaji Number: J203.386K
• Wikidata: Q27145307
• ChEMBL ID: CHEMBL24745
• Mol file: 1136-89-6.mol

Synonyms:1-naphthyl phosphate;alpha-naphthyl phosphate;alpha-naphthylphosphate;naphthyl phosphate

Chemical Property of 1-Naphthyl phosphate

Chemical Property:

• Appearance/Colour: slightly turbid, colorless
• Vapor Pressure: 1.85E-14mmHg at 25°C
• Melting Point: 157-159 °C
• Refractive Index: 1.712
• Boiling Point: 451 °C at 760 mmHg
• PKA: 1.25±0.30(Predicted)
• Flash Point: 226.6 °C
• PSA: 76.57000
• Density: 1.492 g/cm³
• LogP: 2.31130
• Storage Temp.: 2-8°C
• Solubility.: H2O: 0.1 g/mL, slightly turbid, colorless
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 224.02384576
• Heavy Atom Count: 15
• Complexity: 262

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Naphthyl Phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2OP(=O)(O)O
• Uses: 1-Naphthyl Phosphate functions as a substrate in the optimized bioassay for mucin 1 detection in serum samples, and in the analysis and detection of lysozymes in real samples. It also functions as a substrate in the development of automated flow-based electrochemical aptasensor for online detection of ochratoxin A.

Technology Process of 1-Naphthyl phosphate

There total 9 articles about 1-Naphthyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

tri-1-naphthyl phosphate (4004-51-7) → 1,1'-bisnaphthalene (604-53-5) + 1-naphthylphosphoric acid (1136-89-6)

Guidance literature:

With dichloro-acetic acid; In acetonitrile; Quantum yield; Rate constant; Mechanism; Irradiation;

DOI:10.1021/jo9805706

Reference yield:

di-1-naphthyl methylphosphate (173313-35-4) → 1,1'-bisnaphthalene (604-53-5) + 1-naphthylphosphoric acid (1136-89-6)

Guidance literature:

With 9,10-Dicyanoanthracene; In acetonitrile; Irradiation;

DOI:10.1039/a702230a

Reference yield:

tri-1-naphthyl phosphate (4004-51-7) → 1,1'-bisnaphthalene (604-53-5) + 1-naphthylphosphoric acid (1136-89-6) + 1-naphthyl 1,2'-binaphthalene-1'-yl phosphate

Guidance literature:

In acetonitrile; for 0.333333h; Mechanism; Quantum yield; Irradiation; other tri-1-naphthyl phosphate analogs;

upstream raw materials:

1-naphthyl dichlorophosphate

tri-1-naphthyl phosphate

di-1-naphthyl methylphosphate

α-naphthoxydichlorophosphine

Downstream raw materials:

α-naphthol

phosphoric acid

diethyl naphthalen-1-yl phosphate

bis((1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl) naphthalen-1-yl phosphate

Refernces

• 1、 Nakamura, Mitsunobu,Dohno, Reizo,Majima, Tetsuro. "Photoinduced electron-transfer reactions of tri-1-naphthyl phosphate and di-1-naphthyl methylphosphonate sensitised by 9,10-dicyanoanthracene". . p. 1291 - 1292. Retrieved 1997.
• 2、 Zhang, Youlai,Tanimoto, Hiroki,Nishiyama, Yasuhiro,Morimoto, Tsumoru,Kakiuchi, Kiyomi. "Novel photolabile protecting group for phosphate compounds". scheme or table. p. 367 - 370. Retrieved 2012/03/11.