Pterin-6-carboxylic acid

Base Information

• Chemical Name: Pterin-6-carboxylic acid
• CAS No.: 948-60-7
• Molecular Formula: C7H5 N5 O3
• Molecular Weight: 207.148
• Hs Code.: 2933990090
• Mol file: 948-60-7.mol

Synonyms:6-Pteridinecarboxylicacid, 2-amino-1,4-dihydro-4-oxo- (8CI,9CI);6-Pteridinecarboxylic acid,2-amino-4-hydroxy- (6CI);6-Carboxypterin;NSC 96893;Pterin-6-carboxylic acid;Ranachrome 5;

Chemical Property of Pterin-6-carboxylic acid

Chemical Property:

• Melting Point: 300 °C (approx, decomp)
• Boiling Point: 608.7 °C at 760 mmHg
• PKA: 5.40±0.20(Predicted)
• Flash Point: 322 °C
• PSA: 134.85000
• Density: 2.16 g/cm³
• LogP: -0.42530
• Storage Temp.: 2-8°C
• Solubility.: Aqueous Acid (Very Slightly), Aqueous Base (Very Slightly, Heated)

Purity/Quality:

99% ^*data from raw suppliers

Pterine-6-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Pterine-6-carboxylic Acid is a degradation product of Folic acid (F680300).

Technology Process of Pterin-6-carboxylic acid

There total 33 articles about Pterin-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-formylpterin (712-30-1) → pterine-6-carboxylic acid (948-60-7)

Guidance literature:

With potassium hydroxide; potassium permanganate;

DOI:10.1007/BF01418018

Reference yield: 79.0%

2,4-diamino-pteridine-6-carboxylic acid (716-74-5) → pterine-6-carboxylic acid (948-60-7)

Guidance literature:

With sodium hydroxide; at 65 - 68 ℃; for 2h;

Reference yield: 73.0%

7,8-dihydro-6-(2-furyl)pterin (120930-09-8) → pterine-6-carboxylic acid (948-60-7)

Guidance literature:

With sodium hydroxide; potassium permanganate; at 50 - 55 ℃; for 0.5h;

upstream raw materials:

2,5,6-triamino-3,4-dihydro-4-pyrimidinone

ethyl 2-bromo-3,3-diethoxypropionate

6-formylpterin

7,8-dihydro-6-(2-furyl)pterin

Downstream raw materials:

2-aminopteridin-4(3H)-one

Refernces

• 1、 Hirakawa, Kazutaka,Morimoto, Shu. "Electron transfer mediated decomposition of folic acid by photoexcited dimethoxophosphorus(V)porphyrin". . p. 1 - 6. Retrieved 2016.
• 2、 Forrest et al.. "-". . p. 1005,1009. Retrieved 1960.
• 3、 Santos, Willy G.,Scurachio, Regina S.,Cardoso, Daniel R.. "Photochemical behavior of Safranine-Riboflavin complex in the degradation of folic acid". . p. 32 - 39. Retrieved 2014.
• 4、 Laura Dántola,Zurbano, Beatriz N.,Thomas, Andrés H.. "Photoinactivation of tyrosinase sensitized by folic acid photoproducts". . p. 172 - 179. Retrieved 2015/06/25.