Unii-Y29K672etf

Base Information

• Chemical Name: Unii-Y29K672etf
• CAS No.: 523-98-8
• Molecular Formula: C₁₀H₁₃N₄O₉P
• Molecular Weight: 364.208
• Mol file: 523-98-8.mol

Synonyms:Y29K672ETF;UNII-Y29K672ETF;SCHEMBL2217345

Chemical Property of Unii-Y29K672etf

Chemical Property:

• PSA: 215.98000
• LogP: -1.15760
• XLogP3: -4
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 4
• Exact Mass: 364.04201500
• Heavy Atom Count: 24
• Complexity: 585

Purity/Quality:

98%min ^*data from raw suppliers

XANTHOSINE-5'-MONOPHOSPHATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)NC(=O)NC2=O
• Isomeric SMILES: C1=NC2=C(N1C3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)NC(=O)NC2=O

Technology Process of Unii-Y29K672etf

There total 12 articles about Unii-Y29K672etf which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

xanthosine (146-80-5) → XMP (523-98-8,57282-68-5)

Guidance literature:

xanthosine; With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; trichlorophosphate; at 20 ℃; for 0.25h; Flow reactor; Green chemistry;

With water; at 20 ℃; Temperature; chemoselective reaction; Flow reactor; Green chemistry;

DOI:10.1021/op5002066

Reference yield: 19.0%

L-xanthosine (146-80-5,6253-54-9,70332-31-9) → L-xanthosine 5’-monophosphate (523-98-8,57282-68-5)

Guidance literature:

L-xanthosine; With trimethyl phosphite; trichlorophosphate;

With tetraethylammonium bromide; In water;

DOI:10.1002/cbic.201200503

Reference yield:

Guanosine 5'-monophosphate (85-32-5) → 2-Chlor-inosin-5'-phosphat (26550-86-7) + XMP (523-98-8,57282-68-5) + Oxanosine 5'-monophosphate

Guidance literature:

With sodium acetate; sodium chloride; sodium nitrite; In water; at 37 ℃; for 2h; pH=3.2; Product distribution;

DOI:10.1016/S0968-0896(01)00173-0

upstream raw materials:

[5']inosinic acid

Guanosine 5'-monophosphate

nicotinamide adenine dinucleotide

5-phosphoribosyl-1-pyrophosphate

Downstream raw materials:

L-glutamic acid

Guanosine 5'-monophosphate

5'-adenosine monophosphate

guanosine 5'-monophosphate

Refernces

• 1、 Dairaku, Issei,Han, Yunkyung,Yanaka, Noriyuki,Kato, Norihisa. "Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents". . p. 185 - 187. Retrieved 2010.
• 2、 Zhu, Chenjie,Tang, Chenglun,Cao, Zhi,He, Wei,Chen, Yong,Chen, Xiaochun,Guo, Kai,Ying, Hanjie. "Fully automated continuous meso-flow synthesis of 5′-nucleotides and deoxynucleotides". . p. 1575 - 1581. Retrieved 2015/02/19.