4-(1-Naphthylmethyl)toluene

Base Information

• Chemical Name: 4-(1-Naphthylmethyl)toluene
• CAS No.: 20204-71-1
• Molecular Formula: C18H16
• Molecular Weight: 232.325
• DSSTox Substance ID: DTXSID001287459
• Nikkaji Number: J428.478J
• Mol file: 20204-71-1.mol

Synonyms:1-[(4-methylphenyl)methyl]naphthalene;4-(1-Naphthylmethyl)toluene;DTXSID001287459;LS-94796;20204-71-1

Chemical Property of 4-(1-Naphthylmethyl)toluene

Chemical Property:

• XLogP3: 5.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 232.125200510
• Heavy Atom Count: 18
• Complexity: 249

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)CC2=CC=CC3=CC=CC=C32

Technology Process of 4-(1-Naphthylmethyl)toluene

There total 19 articles about 4-(1-Naphthylmethyl)toluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-Fluoronaphthalene (321-38-0) + 4-Methylbenzyl chloride (104-82-5) → α-(4-methylbenzyl)naphthalene (20204-71-1)

Guidance literature:

With C₂₃H₄₀Br₂N₂NiO₅P; magnesium; In tetrahydrofuran; at 65 ℃; for 10h; Inert atmosphere;

Reference yield: 97.0%

4-Methylbenzyl chloride (104-82-5) + 1-Chloronaphthalene (90-13-1) → α-(4-methylbenzyl)naphthalene (20204-71-1)

Guidance literature:

With C₂₃H₄₀Br₂N₂NiO₅P; magnesium; In tetrahydrofuran; at 50 ℃; for 1h; Inert atmosphere;

Reference yield: 96.0%

4-methylphenylboronic acid (5720-05-8) + N,N,N-trimethyl-1-(naphthalene-1-yl)methanaminium iodide (116265-10-2) → α-(4-methylbenzyl)naphthalene (20204-71-1)

Guidance literature:

With potassium phosphate; (NC₅H₃(N₂C₇H₄(CH₂)3CH₃)2)NiBr⁽¹⁺⁾*Br^(1-)=Ni(NC₅H₃(N₂C₇H₄(CH₂)3CH₃)2)Br₂; triphenylphosphine; In 1,4-dioxane; at 80 ℃; for 24h; Schlenk technique;

DOI:10.1016/j.cclet.2016.09.006

upstream raw materials:

naphthalene

1-Chloromethylnaphthalene

1-naphthaldehyde

toluene

Downstream raw materials:

(4-methylphenyl)(1-naphthyl)methanone

Refernces

• 1、 Ma, Xufeng,Wang, Han,Liu, Yao,Zhao, Xing,Zhang, Jun. "Mixed Alkyl/Aryl Diphos Ligands for Iron-Catalyzed Negishi and Kumada Cross Coupling Towards the Synthesis of Diarylmethane". . p. 5134 - 5140. Retrieved 2021/11/16.
• 2、 -. "Preparation and application of blended nickel (II) complex with bisoxazoline derived azacyclo-carbene ligand and phosphite ester ligand". Paragraph 0058-0059. . Retrieved 2019/10/17.