Trifluoroacetic acid 3-methoxyphenyl ester

Base Information

• Chemical Name: Trifluoroacetic acid 3-methoxyphenyl ester
• CAS No.: 31083-16-6
• Molecular Formula: C9H7F3O3
• Molecular Weight: 220.148
• Mol file: 31083-16-6.mol

Synonyms:Trifluoro-acetic acid 3-methoxy-phenyl ester;

Chemical Property of Trifluoroacetic acid 3-methoxyphenyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 2.16290

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoroacetic acid 3-methoxyphenyl ester

There total 2 articles about Trifluoroacetic acid 3-methoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxybenzenediazonium tetrafluoroborate + trifluoroacetic acid (76-05-1) → 1-fluoro-3-methoxybenzene (456-49-5) + m-Methoxyphenyltrifluoracetat (31083-16-6)

Guidance literature:

Heating;

DOI:10.1246/bcsj.75.789

Reference yield:

→ m-Methoxyphenyltrifluoracetat (31083-16-6)

Guidance literature:

entspr. Aryl-bleitriacetat, Trifluoressigsaeure, Tab.I, S.854;

DOI:10.1016/S0040-4039(01)82352-2

Reference yield: 50.0%

m-Methoxyphenyltrifluoracetat (31083-16-6) + 1-Isopropoxy-1-(trimethylsiloxy)cyclopropane (84098-44-2) → 3-(3-Methoxy-phenyl)-propionic acid isopropyl ester (113777-15-4)

Guidance literature:

bis(η3-allyl-μ-chloropalladium(II)); triphenylphosphine; In benzene; at 100 ℃; for 6h;

DOI:10.1021/ja00218a048

upstream raw materials:

trifluoroacetic acid

Downstream raw materials:

3-(3-Methoxy-phenyl)-propionic acid isopropyl ester

Refernces