1-Chloro-10-fluorodecane

Base Information

• Chemical Name: 1-Chloro-10-fluorodecane
• CAS No.: 334-62-3
• Molecular Formula: C10H20ClF
• Molecular Weight: 194.75
• Hs Code.: 2903799090
• DSSTox Substance ID: DTXSID10187038
• Nikkaji Number: J40.811E
• Wikidata: Q83058564
• Mol file: 334-62-3.mol

Synonyms:1-Chloro-10-fluorodecane;334-62-3;DECANE, 1-CHLORO-10-FLUORO-;10-Fluorodecyl chloride;1-Fluoro-10-chlorodecane;BRN 1738599;4-01-00-00469 (Beilstein Handbook Reference);C10H20ClF;1-chloro-10-fluoro-decane;C10-H20-Cl-F;DTXSID10187038;AKOS040751490;LS-59284

Chemical Property of 1-Chloro-10-fluorodecane

Chemical Property:

• Vapor Pressure: 0.0356mmHg at 25°C
• Refractive Index: 1.4333
• Boiling Point: 249.8°Cat760mmHg
• Flash Point: 110.2°C
• PSA: 0.00000
• Density: 0.925g/cm³
• LogP: 4.31550
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 9
• Exact Mass: 194.1237565
• Heavy Atom Count: 12
• Complexity: 76.2

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCCCl)CCCCF

Technology Process of 1-Chloro-10-fluorodecane

There total 3 articles about 1-Chloro-10-fluorodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1-chloro-10-iododecane (57152-87-1) → 1-chloro-10-fluorodecane (334-62-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In dichloromethane; at 20 ℃; Electrochemical reaction;

Reference yield:

10-chlorodecanol (51309-10-5) → 1-chloro-10-fluorodecane (334-62-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaI; chlorotrimethylsilane

2: 68 percent / p-iodotoluene difluoride; Et₃N-4HF / CH₂Cl₂ / 20 °C

With chloro-trimethyl-silane; 4-(difluoroiodo)toluene; triethylamine tris(hydrogen fluoride); sodium iodide; In dichloromethane;

DOI:10.1016/S0040-4020(01)00201-0

Reference yield:

10-fluoro-decan-1-ol (334-64-5) → 1-chloro-10-fluorodecane (334-62-3)

Guidance literature:

With thionyl chloride;

DOI:10.1111/j.1365-2621.2001.tb11339.x

upstream raw materials:

10-fluoro-decan-1-ol

1-chloro-10-iododecane

10-chlorodecanol

Downstream raw materials:

11-fluoroundecanoic acid

ethyl 11-fluoroundecanoate

Refernces

• 1、 Sawaguchi, Masanori,Ayuba, Shinichi,Nakamura, Yutaka,Fukuhara, Tsuyoshi,Hara, Shoji,Yoneda, Norihiko. "Electrochemical fluorodeiodination of alkyl iodides". . p. 999 - 1000. Retrieved 2007/10/03.