Bis[4-(2-hydroxyethoxy)phenyl] sulfone

Base Information

• Chemical Name: Bis[4-(2-hydroxyethoxy)phenyl] sulfone
• CAS No.: 27205-03-4
• Molecular Formula: C16H18O6S
• Molecular Weight: 338.381
• Hs Code.: 29094990
• European Community (EC) Number: 248-320-1
• NSC Number: 15880
• DSSTox Substance ID: DTXSID70181678
• Nikkaji Number: J31.795K
• Wikidata: Q83052302
• Mol file: 27205-03-4.mol

Synonyms:27205-03-4;Bis[4-(2-hydroxyethoxy)phenyl] sulfone;Bis[4-(2-hydroxyethoxy)phenyl]sulfone;4-(2-Hydroxyethoxy)phenyl Sulfone;Ethanol, 2,2'-[sulfonylbis(4,1-phenyleneoxy)]bis-;2-[4-[4-(2-hydroxyethoxy)phenyl]sulfonylphenoxy]ethanol;2,2'-((Sulfonylbis(4,1-phenylene))bis(oxy))diethanol;EINECS 248-320-1;2,2-((Sulfonylbis(4,1-phenylene))bis(oxy))diethanol;2,2'-(Sulphonylbis(4,1-phenyleneoxy))bisethanol;2,2'-[sulphonylbis(4,1-phenyleneoxy)]bisethanol;Ethanol, 2,2'-(sulfonylbis(4,1-phenyleneoxy))bis-;C16H18O6S;NSC15880;SCHEMBL34118;DTXSID70181678;C16-H18-O6-S;MFCD00130282;NSC 15880;NSC-15880;AKOS015856807;bis [4-(2-hydroxyethoxy)phenyl]sulfone;bis[4-(2-hydroxyethoxy) phenyl]sulfone;AS-69030;4,4'-Di(2-Hydroxyethoxy)diphenyl Sulfone;bis [4-(2-hydroxyethoxy) phenyl] sulfone;B1590;Bis[4-(2-hydroxyethoxy)phenyl] sulfone, 95%;F87428;A854492;2,2'-[sulfonylbis(benzene-4,1-diyloxy)]diethanol;2,2'-(4,4'-sulfonylbis(4,1-phenylene)bis(oxy))diethanol;2-{4-[4-(2-hydroxyethoxy)benzenesulfonyl]phenoxy}ethan-1-ol;2,2'-((SULFONYLBIS(4,1-PHENYLENE))BIS(OXY))BIS(ETHAN-1-OL)

Chemical Property of Bis[4-(2-hydroxyethoxy)phenyl] sulfone

Chemical Property:

• Vapor Pressure: 2.08E-14mmHg at 25°C
• Melting Point: 179-183 °C(lit.)
• Refractive Index: 1.587
• Boiling Point: 582.5 °C at 760 mmHg
• PKA: 13.76±0.10(Predicted)
• Flash Point: 306.1 °C
• PSA: 101.44000
• Density: 1.333 g/cm³
• LogP: 2.34240
• Solubility.: almost transparency in hot Methanol
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 338.08240946
• Heavy Atom Count: 23
• Complexity: 382

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-[4-[4-(2-Hydroxyethoxy)phenyl]sulfonylphenoxy]ethanol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1OCCO)S(=O)(=O)C2=CC=C(C=C2)OCCO

Technology Process of Bis[4-(2-hydroxyethoxy)phenyl] sulfone

There total 7 articles about Bis[4-(2-hydroxyethoxy)phenyl] sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.1%

4,4'-sulfonediphenol (80-09-1,59790-00-0) + ethylene glycol (107-21-1) → 2,2’-((sulfonylbis(4,1-phenylene))bis(oxy))bis(ethan-1-ol) (27205-03-4)

Guidance literature:

With tetrabutoxytitanium; aluminum (III) chloride; bismuth; at 150 ℃; for 1h; Temperature; Reagent/catalyst;

Reference yield: 87.0%

[1,3]-dioxolan-2-one (96-49-1) + 4,4'-sulfonediphenol (80-09-1,59790-00-0) → 2,2’-((sulfonylbis(4,1-phenylene))bis(oxy))bis(ethan-1-ol) (27205-03-4)

Guidance literature:

With potassium carbonate; In cyclohexanone; at 150 ℃; for 5h; Inert atmosphere;

Reference yield: 83.0%

4,4'-sulfonediphenol (80-09-1,59790-00-0) + 2-bromoethanol (540-51-2) → 2,2’-((sulfonylbis(4,1-phenylene))bis(oxy))bis(ethan-1-ol) (27205-03-4)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 110 ℃; for 10h;

DOI:10.1002/asia.201900423

upstream raw materials:

oxirane

4,4'-sulfonediphenol

[1,3]-dioxolan-2-one

2-chloro-ethanol

Downstream raw materials:

bis-[4-(2-methanesulfonyloxy-ethoxy)-phenyl]-sulfone

bis-[4-(2-carbamoyloxy-ethoxy)-phenyl]-sulfone

4,4'-bis(chloroethyloxy)diphenylsulfone

Refernces

• 1、 Lotti,Colonna,Fiorini,Finelli,Berti. "Poly(butylene terephthalate) modified with ethoxylated bisphenol S with increased glass transition temperature and improved thermal stability". . p. 904 - 911. Retrieved 2011.
• 2、 -. "Preparation method of bis[4-(2-hydroxyethoxy)phenyl] sulphone and derivative of bis[4-(2-hydroxyethoxy)phenyl] sulphone as well as catalyst of bis[4-(2-hydroxyethoxy)phenyl] sulphone and derivative of bis[4-(2-hydroxyethoxy)phenyl] sulphone". Paragraph 0012. . Retrieved 2018/02/04.