Benzenemethanamine, N,N-diethyl-a-methylene-

Base Information

• Chemical Name: Benzenemethanamine, N,N-diethyl-a-methylene-
• CAS No.: 59590-86-2
• Molecular Formula: C12H17N
• Molecular Weight: 175.274
• Mol file: 59590-86-2.mol

Synonyms:N,N-diethyl-1-phenylethanamine;N,N-diethyl-1-phenylethen-1-amine;Diethyl-(1-phenyl-vinyl)-amine;N-(1-phenylethen-1-yl)diethylamine;N,N-diethyl-1-phenylethene-1-amine;N,N-diethyl-1-phenylethenyl-1-amine;N,N-diethyl-N-(1-phenylethenyl)amine;

Chemical Property of Benzenemethanamine, N,N-diethyl-a-methylene-

Chemical Property:

• Boiling Point: 60 - 61 °C (1 mmHg)
• PSA: 3.24000
• Density: 0.912±0.06 g/cm3(Predicted)
• LogP: 2.99910

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, N,N-diethyl-a-methylene-

There total 7 articles about Benzenemethanamine, N,N-diethyl-a-methylene- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

diethylamine (109-89-7) + acetophenone (98-86-2) → 1-diethylaminostyrene (59590-86-2)

Guidance literature:

With titanium tetrachloride; In hexane; at 0 - 20 ℃; for 24.5h; Inert atmosphere;

DOI:10.1021/ol901891u

Reference yield: 71.2%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + diethylamine (109-89-7) → 1-diethylaminostyrene (59590-86-2) + (E)-N,N-diethyl-2-phenylethen-1-amine (82489-29-0)

Guidance literature:

With oxygen; triethylamine; PS-[VO(sal-cys)*DMF]; In acetonitrile; at 75 ℃; for 4h;

DOI:10.1002/ejic.200700662

Reference yield:

diethylamine (109-89-7) + phenylacetylene (536-74-3) → 1-diethylaminostyrene (59590-86-2)

Guidance literature:

With AuC₃₄H₄₇N⁽¹⁺⁾*B(C₆F₅)4^(1-)=(AuC₃₄H₄₇N)(B(C₆F₅)4); In benzyl methyl ether; benzene-d6; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1002/chem.200802626

upstream raw materials:

acetophenone

diethylamine

styrene

phenylacetylene

Downstream raw materials:

ethyl 2-methyl-4-oxo-4-phenyl-butanoate

(R)-1,3-diphenylpent-4-yn-1-one

Refernces

• 1、 Hu, Bei,Chen, Haixia,Liu, Yan,Dong, Wuheng,Ren, Kai,Xie, Xiaomin,Xu, Hao,Zhang, Zhaoguo. "Visible light-induced intermolecular radical addition: Facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines". supporting information. p. 13547 - 13550. Retrieved 2015/01/09.
• 2、 Hu, Yue,Norton, Jack R.. "Kinetics and thermodynamics of H-/H?/H+ transfer from a rhodium(III) hydride". . p. 5938 - 5948. Retrieved 2014/05/20.