N,N-Diphenylformamide

Base Information

• Chemical Name: N,N-Diphenylformamide
• CAS No.: 607-00-1
• Molecular Formula: C13H11 N O
• Molecular Weight: 197.236
• Hs Code.: 2924299090
• European Community (EC) Number: 210-129-6
• NSC Number: 3864
• UNII: FF0X003442
• DSSTox Substance ID: DTXSID9022077
• Nikkaji Number: J95.447K
• Wikidata: Q27277952
• Mol file: 607-00-1.mol

Synonyms:diphenylformamide

Chemical Property of N,N-Diphenylformamide

Chemical Property:

• Vapor Pressure: 0.000105mmHg at 25°C
• Melting Point: 69-73 °C(lit.)
• Refractive Index: 1.6050 (estimate)
• Boiling Point: 337 °C762 mm Hg(lit.)
• PKA: -2.73±0.50(Predicted)
• Flash Point: 155.6°C
• PSA: 20.31000
• Density: 1.151g/cm³
• LogP: 3.61700
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 197.084063974
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N-Diphenylformamide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Aromatics (Nitrogen)
• Canonical SMILES: C1=CC=C(C=C1)N(C=O)C2=CC=CC=C2

Technology Process of N,N-Diphenylformamide

There total 39 articles about N,N-Diphenylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

carbon dioxide (124-38-9,18923-20-1) + diphenylamine (122-39-4) → diphenylformamide (607-00-1)

Guidance literature:

With copper(II) acetate dihydrate; phenylsilane; 1,2-bis-(diphenylphosphino)ethane; In toluene; at 25 ℃; for 4h; under 760.051 Torr;

DOI:10.1039/c6ra05199e

Reference yield: 98.0%

formic acid (64-18-6) + diphenylamine (122-39-4) → diphenylformamide (607-00-1)

Guidance literature:

With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; In neat (no solvent); at 50 ℃; for 0.75h;

DOI:10.1016/j.tetlet.2013.07.033

Reference yield: 98.0%

4-chlorophenyl formate (1988-22-3) + diphenylamine (122-39-4) → diphenylformamide (607-00-1)

Guidance literature:

In neat (no solvent); at 20 ℃; for 2h;

DOI:10.1080/00397911.2016.1255334

upstream raw materials:

2-(diphenylamino)-2-oxoacetic acid

oxalic acid

diphenylamine

formic acid

Downstream raw materials:

diphenylamine

isovaleraldehyde

1,1-Diphenylmethanol

benzaldehyde

Refernces

• 1、 Dhawan, Sanjeev,Girase, Pankaj Sanjay,Kumar, Vishal,Karpoormath, Rajshekhar. "HCl-mediated transamidation of unactivated formamides using aromatic amines in aqueous media". . p. 3729 - 3739. Retrieved 2021/10/14.
• 2、 Azad, Shiyana,Bal, Rajaram,Bhattacharjee, Sudip,Bhaumik, Asim,Chongdar, Sayantan. "Selective N-formylation of amines catalysed by Ag NPs festooned over amine functionalized SBA-15 utilizing CO2 as C1 source". . . Retrieved 2021/11/08.