2-OXOBUTANALDEHYDE

Base Information

• Chemical Name: 2-OXOBUTANALDEHYDE
• CAS No.: 4417-81-6
• Molecular Formula: C4H6O2
• Molecular Weight: 86.0904
• Hs Code.: 2914400090
• Mol file: 4417-81-6.mol

Synonyms:Butyraldehyde,2-oxo- (6CI,7CI,8CI);2-Oxobutanal;2-Oxobutyraldehyde;Ethanedione, ethyl-;Ethylglyoxal;a-Ketobutanal;

Chemical Property of 2-OXOBUTANALDEHYDE

Chemical Property:

• Vapor Pressure: 52.9mmHg at 25°C
• Refractive Index: 1.383
• Boiling Point: 91.8 °C at 760 mmHg
• Flash Point: 16.4 °C
• PSA: 34.14000
• Density: 0.967 g/cm³
• LogP: 0.16440

Purity/Quality:

98%Min ^*data from raw suppliers

2-OXOBUTANALDEHYDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Oxobutanal was used as a reagent in the preparation of dipeptidyl enoates which may act as potent rhodesain inhibitors. It was under investigation as a mutagen that reacts with 2''-deoxyguanosine in model systems of lipid peroxidation to form an adduct.

Technology Process of 2-OXOBUTANALDEHYDE

There total 26 articles about 2-OXOBUTANALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

butanone (78-93-3) → ethylglyoxal (4417-81-6)

Guidance literature:

With selenium(IV) oxide;

Reference yield:

ethylglyoxal dimethylacetal (6342-57-0) → ethylglyoxal (4417-81-6)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01597a083

Reference yield:

1-methylthio-1-butanol-2-one (109902-07-0) → ethylglyoxal (4417-81-6)

Guidance literature:

With copper diacetate; In dichloromethane; at 23 ℃; for 1h;

DOI:10.1039/c2cc31230a

upstream raw materials:

ethanol

N-chloro-N,N-dibutylamine

2-ethyl-pent-2-enal

ethylglyoxal dimethylacetal

Downstream raw materials:

2-hydroxyimino-butyraldehyde oxime

2-oxo-butyraldehyde-(4-nitro-phenylhydrazone)

2-phenylhydrazono-butyraldehyde phenylhydrazone

ethylglyoxal 2,4-dinitrophenylhydrazone

Refernces

• 1、 Schieberle, Peter. "Quantitation of Important Roast-Smelling Odorants in Popcorn by Stable Isotope Dilution Assays and Model Studies on Flavor Formation during Popping". . p. 2442 - 2448. Retrieved 1995.
• 2、 De Bruin, Bas,De Zwart, Felix J.,Li, Zirui,Mathew, Simon,Wolzak, Lukas A.,Zhou, Minghui. "Catalytic Synthesis of 1 H-2-Benzoxocins: Cobalt(III)-Carbene Radical Approach to 8-Membered Heterocyclic Enol Ethers". supporting information. p. 20501 - 20512. Retrieved 2021/12/03.
• 3、 Hayashi, Yujiro,Yasui, Yusuke,Kojima, Masahiro,Kawamura, Tsuyoshi,Ishikawa, Hayato. "Diarylprolinol in an asymmetric aldol reaction of an α-alkyl-α- oxo aldehyde as an electrophile". supporting information; experimental part. p. 4570 - 4572. Retrieved 2012/06/01.