Ethyl L-lysinate dihydrochloride

Base Information

• Chemical Name: Ethyl L-lysinate dihydrochloride
• CAS No.: 3844-53-9
• Molecular Formula: C8H18 N2 O2 . 2 Cl H
• Molecular Weight: 247.165
• Hs Code.: 29224999
• European Community (EC) Number: 223-340-3
• Mol file: 3844-53-9.mol

Synonyms:3844-53-9;L-Lysine ethyl ester dihydrochloride;H-Lys-OEt.2HCl;Ethyl L-lysinate dihydrochloride;ethyl (2S)-2,6-diaminohexanoate dihydrochloride;L-Lysine, ethyl ester, dihydrochloride;Ethyl L-lysinate HCl;ethyl 2,6-bis(azanyl)hexanoate hydrochloride;ethyl (2S)-2,6-diaminohexanoate;dihydrochloride;(S)-Ethyl 2,6-diaminohexanoate dihydrochloride;lysine ethyl ester dihydrochloride;H-Lys-OEt inverted exclamation mark currency2HCl;EINECS 223-340-3;MFCD00039068;H-LYS-OET2HCL;H-Lys-OEt dihydrochloride;SCHEMBL213479;ethyl 2,6-diaminohexanoate 2hcl;DZIYAIZKJOHVQC-KLXURFKVSA-N;AKOS015908343;AM81965;GS-3471;NSC 162742;AC-19222;A824156;J-300190;W-106484;L-Lysine ethyl ester dihydrochloride, >=99.0% (AT)

Chemical Property of Ethyl L-lysinate dihydrochloride

Chemical Property:

• Appearance/Colour: White Powder
• Vapor Pressure: 0.0112mmHg at 25°C
• Melting Point: ~150 °C (dec.)
• Boiling Point: 261.9 °C at 760 mmHg
• Flash Point: 97.3 °C
• PSA: 78.34000
• Density: g/cm³
• LogP: 3.01040
• Storage Temp.: −20°C
• Sensitive.: Hygroscopic
• Solubility.: Aqueous Acid (Slightly, Heated), Water (Sparingly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 246.0901833
• Heavy Atom Count: 14
• Complexity: 128

Purity/Quality:

99% ^*data from raw suppliers

L-Lysine ethyl ester dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 36/37/38:
• Hazard Codes: 36/37/38:
• Statements: 36/37/38
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=O)C(CCCCN)N.Cl.Cl
• Isomeric SMILES: CCOC(=O)[C@H](CCCCN)N.Cl.Cl
• Uses: L-?Lysine Ethyl Ester Dihydrochloride is a reagent used in the preparation of myxochelin which has been shown to possess strong anti-tumor activity.

Technology Process of Ethyl L-lysinate dihydrochloride

There total 3 articles about Ethyl L-lysinate dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

ethanol (64-17-5) + L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) → L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

With thionyl chloride; Reflux;

DOI:10.1016/j.cclet.2010.11.016

Reference yield:

ethanol (64-17-5) → L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

With hydrogenchloride;

DOI:10.1246/bcsj.11.208

Reference yield:

→ L-lysine ethyl ester dihydrochloride (3844-53-9,5721-12-0)

Guidance literature:

upstream raw materials:

ethanol

L-Lysine hydrochloride

Downstream raw materials:

myxochelin A

C₅₄H₇₂N₆O₁₄

Boc-Lys(Boc)-OH

N,N-bis-Cbz-L-lysinol

Refernces

• 1、 Alborzi, Ali Reza,Zahmatkesh, Saeed,Zare, Karim,Sadeghi, Javad. "Optically active: Microwave-assisted synthesis and characterization of l-lysine-derived poly (amide-imide)s". experimental part. p. 485 - 494. Retrieved 2012/04/10.
• 2、 -. "Racemization of an optically active lysine alkyl ester". . . Retrieved 2008/06/13.