Lactofen

Base Information

• Chemical Name: Lactofen
• CAS No.: 77501-63-4
• Deprecated CAS: 83513-60-4,143956-87-0,143956-87-0
• Molecular Formula: C19H15ClF3NO7
• Molecular Weight: 461.779
• Hs Code.: 29189900
• UN Number: 3077
• UNII: L44N8UV47O
• DSSTox Substance ID: DTXSID7024160
• Nikkaji Number: J138.370A
• Wikipedia: Lactofen
• Wikidata: Q6469021
• ChEMBL ID: CHEMBL1243178
• Mol file: 77501-63-4.mol

Synonyms:1'-(carboethoxy)ethyl 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoate;lactofen

Chemical Property of Lactofen

Chemical Property:

• Appearance/Colour: Dark brown to tan solid
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 43.9 - 45.5 degreesoC
• Refractive Index: 1.532
• Boiling Point: 494 °C at 760 mmHg
• Flash Point: 252.6 °C
• PSA: 107.65000
• Density: 1.42 g/cm³
• LogP: 5.69090
• Storage Temp.: 0-6°C
• Water Solubility.: 110μg/L at 20℃
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 8
• Exact Mass: 461.0489140
• Heavy Atom Count: 31
• Complexity: 657
• Transport DOT Label: Class 9

Purity/Quality:

99.9% ^*data from raw suppliers

Lactofen(>85%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 21-51/53
• Safety Statements: 36/37-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Herbicides, Protox-Inhibiting
• Canonical SMILES: CCOC(=O)C(C)OC(=O)C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-]
• Uses: Lactofen is a complex ester derivative of Acifluoren, a diphenyl ether herbicide. Lactofen can be used in postemergence applications and is commonly used as foliar spray. Lactofen is used in agriculture to control broadleaved weeds in soybean, cereals, potatoes and peanuts.

Technology Process of Lactofen

There total 3 articles about Lactofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1'-(ethoxycarbonyl)ethyl 3-(2-chloro-4-trifluoromethylphenoxy)benzoate (88185-22-2) → 1-(carboethoxy)ethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate (77501-63-4)

Guidance literature:

With sulfuric acid; nitric acid; acetic anhydride; In dichloromethane;

Reference yield:

acifluorfen (50594-66-6,94128-04-8) + 2-chloro-propanoic acid, ethyl ester (535-13-7) → 1-(carboethoxy)ethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate (77501-63-4)

Guidance literature:

With potassium hydroxide; In ethyl acetate; Solvent; Reagent/catalyst; Heating;

Reference yield:

→ 1-(carboethoxy)ethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate (77501-63-4)

Guidance literature:

upstream raw materials:

1'-(ethoxycarbonyl)ethyl 3-(2-chloro-4-trifluoromethylphenoxy)benzoate

acifluorfen

2-chloro-propanoic acid, ethyl ester

Downstream raw materials:

1-(carboxy)ethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate

ethanol

Refernces

• 1、 -. "Treatment of skin conditions by use of PPAR alpha activators". . . Retrieved 2008/06/13.
• 2、 -. "Alkylsiloxanes as adjuvants for agriculture". . . Retrieved 2008/06/13.