Sulconazole nitrate

Base Information

• Chemical Name: Sulconazole nitrate
• CAS No.: 61318-91-0
• Molecular Formula: C18H16Cl3N3O3
• Molecular Weight: 460.768
• Hs Code.: 2933290000
• European Community (EC) Number: 624-696-6
• NSC Number: 757849
• UNII: 1T89100D5U
• DSSTox Substance ID: DTXSID2045490
• Wikidata: Q27252867
• NCI Thesaurus Code: C47733
• RXCUI: 56798
• Pharos Ligand ID: P5LLT4F3P3PG
• ChEMBL ID: CHEMBL1200348
• Mol file: 61318-91-0.mol

Synonyms:1-(beta-(4''-chlorobenzylthio)-2'4'-dichlorophenethyl)imidazole;Exelderm;Myk;sulconazole;sulconazole mononitrate;sulconazole nitrate;sulconazole, mononitrate, (+-)-isomer

Chemical Property of Sulconazole nitrate

Chemical Property:

• Appearance/Colour: White crystalline powder
• Melting Point: 130.5-132℃
• Boiling Point: 558.2 °C at 760 mmHg
• Flash Point: 291.4 °C
• PSA: 109.17000
• LogP: 6.69350
• Storage Temp.: room temp
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 458.997796
• Heavy Atom Count: 28
• Complexity: 404

Purity/Quality:

99% ^*data from raw suppliers

Sulconazole nitrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]
• Uses: Sulconazole Nitrate is an antifungal agent which prevents fungal growth by inhibiting sterol synthesis.

Technology Process of Sulconazole nitrate

There total 2 articles about Sulconazole nitrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-1-(2,4-dichlorophenyl)-2-(1H-imidazole-1-yl)ethane (46503-49-5) + (4-chlorophenyl)methanethiol (6258-66-8) → sulconazole nitrate (61318-91-0,82382-23-8)

Guidance literature:

With sodium chloride; In tetrahydrofuran; mineral oil;

Reference yield:

→ sulconazole nitrate (61318-91-0,82382-23-8)

Guidance literature:

upstream raw materials:

1-chloro-1-(2,4-dichlorophenyl)-2-(1H-imidazole-1-yl)ethane

(4-chlorophenyl)methanethiol

Refernces

• 1、 -. "1-[β(R-thio)phenethyl]imidazoles and derivatives thereof". . . Retrieved 2008/06/13.