Calcein Blue

Base Information

• Chemical Name: Calcein Blue
• CAS No.: 54375-47-2
• Molecular Formula: C15H15NO7
• Molecular Weight: 321.287
• Hs Code.: 2934999090
• Nikkaji Number: J209.068F
• Mol file: 54375-47-2.mol

Synonyms:Calcein Blue;54375-47-2;4-Methylumbelliferonemethyleneiminodiacetic Acid;2-[carboxymethyl-[(7-hydroxy-4-methyl-2-oxochromen-8-yl)methyl]amino]acetic acid;2-{(carboxymethyl)[(7-hydroxy-4-methyl-2-oxochromen-8-yl)methyl]amino}acetic a cid;SCHEMBL109411;RJPSHDMGSVVHFA-UHFFFAOYSA-N;MFCD00006867;STL513092;AKOS015915984;CS-7511;AS-56384;HY-101887;FT-0640243;U0001;T72598;4-Methylumbelliferone-8-methyliminodiacetic acid;2,2'-(((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)azanediyl)diacetic acid;2,2'-((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methylazanediyl)diacetic acid;2,2'-{[(7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl]imino}diacetic acid

Chemical Property of Calcein Blue

Chemical Property:

• Appearance/Colour: white to pale yellow powder
• Vapor Pressure: 4.67E-17mmHg at 25°C
• Melting Point: >200℃
• Boiling Point: 636.2 °C at 760 mmHg
• PKA: 1.73±0.10(Predicted)
• Flash Point: 338.6 °C
• PSA: 128.28000
• Density: 1.512 g/cm³
• LogP: 0.77820
• Solubility.: Soluble in water,methanol, dimethyl sulfoxide
• XLogP3: -1.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 321.08485182
• Heavy Atom Count: 23
• Complexity: 514

Purity/Quality:

98%,99%, ^*data from raw suppliers

Calcein Blue ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Other Dyes
• Canonical SMILES: CC1=CC(=O)OC2=C1C=CC(=C2CN(CC(=O)O)CC(=O)O)O
• Uses: Calcein Blue is a metallofluorochromic indicator for EDTA titration of calcium at high pH and copper, nickel and cobalt at low pH.

Technology Process of Calcein Blue

There total 1 articles about Calcein Blue which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cartap (15263-53-3) + Cu(2+)-calcein blue complex → Calcein blue (54375-47-2) + Cu(2+)-cartap complex

Guidance literature:

In aq. buffer; for 0.133333h; pH=8;

DOI:10.5012/bkcs.2014.35.12.3642

Reference yield: 67.0%

Calcein blue (54375-47-2) + nickel(II) acetate tetrahydrate (6018-89-9) → [Ni(4-methylumbelliferone-8-methyleneiminodiacetate)(H2O)2]*2H2O

Guidance literature:

With KOH; In methanol; to soln. of calcein blue and KOH in MeOH soln. of Ni(OAc)2*4H2O in MeOH was added, stirred for 15 min; elem. anal.;

DOI:10.1016/j.ica.2008.09.049

upstream raw materials:

cartap

Refernces