Ethanone,2-bromo-1-(4-fluoro-1-naphthalenyl)-

Base Information

• Chemical Name: Ethanone,2-bromo-1-(4-fluoro-1-naphthalenyl)-
• CAS No.: 388-31-8
• Molecular Formula: C₁₂H₈BrFO
• Molecular Weight: 267.097
• Hs Code.: 2914700090
• Mol file: 388-31-8.mol

Synonyms:1'-Acetonaphthone,2-bromo-4'-fluoro- (6CI,8CI); 1-(a-Bromoacetyl)-4-fluoronaphthalene; 2-Bromo-1-(4-fluoronaphthalen-1-yl)ethanone;NSC 26056

Chemical Property of Ethanone,2-bromo-1-(4-fluoro-1-naphthalenyl)-

Chemical Property:

• Vapor Pressure: 1.96E-05mmHg at 25°C
• Boiling Point: 362.2°Cat760mmHg
• Flash Point: 172.9°C
• PSA: 17.07000
• Density: 1.548g/cm³
• LogP: 3.55650

Purity/Quality:

99%min ^*data from raw suppliers

2-Bromo-1-(4-fluoronaphthalen-1-yl)ethan-1-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone,2-bromo-1-(4-fluoro-1-naphthalenyl)-

There total 4 articles about Ethanone,2-bromo-1-(4-fluoro-1-naphthalenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-fluoro-1-acetonaphthone (316-68-7) → 4-Fluor-ω-brom-1-acetonaphthon (388-31-8)

Guidance literature:

With bromine; In 1,4-dioxane; at 0 - 20 ℃; for 3h;

Reference yield: 100.0%

→ 4-Fluor-ω-brom-1-acetonaphthon (388-31-8)

Guidance literature:

Reference yield:

→ 4-Fluor-ω-brom-1-acetonaphthon (388-31-8)

Guidance literature:

With diethyl ether; bromine; at 35 ℃; zuletzt bei 10-15grad;

DOI:10.1021/jo01171a005

upstream raw materials:

4-fluoro-1-acetonaphthone

Downstream raw materials:

3-bromo-1-[2-(4-fluoro-[1]naphthyl)-2-oxo-ethyl]-pyridinium; bromide

1-(4-Fluoro-naphthalen-1-yl)-2-phenylamino-ethanone

Refernces

• 1、 -. "Heterocyclic Compound". Page/Page column 95-96. . Retrieved 2011/02/26.
• 2、 -. "DIHYDROIMIDAZOTHIAZOLE DERIVATIVES". Page/Page column 22. . Retrieved 2008/06/13.