4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate

Base Information

• Chemical Name: 4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate
• CAS No.: 60311-02-6
• Molecular Formula: C31H30N2O7S2
• Molecular Weight: 606.72
• Hs Code.: 32049090
• Mol file: 60311-02-6.mol

Synonyms:CHEBI:52274;4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate

Chemical Property of 4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate

Chemical Property:

• Appearance/Colour: green to dark green crystalline powder
• Refractive Index: 1.6900 (estimate)
• PSA: 143.81000
• Density: 1.1982 (rough estimate)
• LogP: 4.59910
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: methanol: soluble1mg/mL
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 606.14944365
• Heavy Atom Count: 42
• Complexity: 1450

Purity/Quality:

98%,99%, ^*data from raw suppliers

Sulforhodamine 101 ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=C(C=C(C=C8)S(=O)(=O)[O-])S(=O)(=O)O)CCC7
• Description: Sulforhodamine 101 is a nonfixable red fluorescent dye (excitation max: 586 nm; emission max: 605 nm) that can be used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. It has been reported to induce long-term potentiation of intrinsic neuronal excitability and a long-lasting increase in evoked excitatory postsynaptic potentials in CA1 pyramidal neurons in hippocampal slices.
• Uses: Sulforhodamine 101 is a red fluorescent dye used in the calcium imaging methods in neurophysiological experiments. A red-emitting flurophore used to label astrocytes. Sulforhodamine 101 is a red fluorescent dye used in the calcium imaging methods in neurophysiological experiments.Dyes and metabolites.

Technology Process of 4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate

There total 1 articles about 4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-18-ium-9-yl)-3-sulfobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ sulforhodamine 101 (60311-02-6)

Guidance literature:

Reference yield: 100.0%

sulforhodamine 101 (60311-02-6) → sulforhodamine 101 sulfonyl chloride

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; Cooling with ice;

DOI:10.1021/ja411046j

Reference yield:

maleic anhydride (108-31-6) + sulforhodamine 101 (60311-02-6) → maleiimide (541-59-3,25721-74-8)

Guidance literature:

With sodium acetate; N-ethyl-N,N-diisopropylamine; In methanol; chloroform; acetic anhydride;

Downstream raw materials:

maleiimide

C₃₉H₄₅N₇O₉S₂

Refernces

• 1、 -. "Activatable probes and methods for in vivo gene detection". . . Retrieved 2008/06/13.
• 2、 -. "Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability". . . Retrieved 2008/06/13.