N-(2,3-Epoxypropyl)phthalimide

Base Information Edit

Chemical Name:N-(2,3-Epoxypropyl)phthalimide
CAS No.:5455-98-1
Deprecated CAS:142176-79-2
Molecular Formula:C11H9NO3
Molecular Weight:203.197
Hs Code.:29251900
European Community (EC) Number:226-710-2
NSC Number:7244
UNII:WWD33Z178Q
DSSTox Substance ID:DTXSID00884165
Nikkaji Number:J219D
Wikidata:Q27292950
ChEMBL ID:CHEMBL2141360
Mol file:5455-98-1.mol

Synonyms:5455-98-1;N-(2,3-EPOXYPROPYL)PHTHALIMIDE;N-Glycidylphthalimide;2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione;2,3-Epoxypropylphthalimide;1H-Isoindole-1,3(2H)-dione, 2-(oxiranylmethyl)-;2-(oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione;Denacol EX 731;N-(2,3-Epoxypropyl)-2-phthalimide;(Phthalimidomethyl)oxirane;2-(oxiran-2-ylmethyl)isoindole-1,3-dione;Phthalimide, N-(2,3-epoxypropyl)-;2-(Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione;HSDB 6084;NSC 7244;EINECS 226-710-2;MFCD00005896;BRN 0171277;UNII-WWD33Z178Q;AI3-50961;MLS002638000;WWD33Z178Q;NSC-7244;1H-Isoindole-1,3(2H)-dione, 2-(2-oxiranylmethyl)-;5-21-11-00064 (Beilstein Handbook Reference);(R)-(-)-Glycidyl phthalimide;N-(2,3-Epoxypropan-1-yl)phthalimide;N-(2,3-Epoxypropyl)phthalimide;n-glycidyl phthalimide;2-Oxiranylmethyl-isoindole-1,3-dione;MFCD04973349;MFCD04973350;NSC7244;glycidyl phthalimide;N-(2,3-Epoxypropyl)-o-Phthalimide;Phthalimide,3-epoxypropyl)-;SCHEMBL38819;N(2,3-epoxypropyl)phthalimide;AMY356;CHEMBL2141360;N(2,3-epoxypropyl)-phthalimide;DUILGEYLVHGSEE-UHFFFAOYSA-;DTXSID00884165;N-OXIRANYLMETHYLPHTHALIMIDE;N-(2,3-epoxypropyl)-phthalimide;HMS3093A20;BCP09616;BCP21807;2-(PHTHALIMIDOMETHYL)OXIRANE;2-oxiranylmethylisoindole-1,3-dione;STL223931;AKOS000200970;AKOS016338801;n-(2,3-epoxypropan-1-yl)phthalimide;1H-Isoindole-1, 2-(oxiranylmethyl)-;PB40940;SB45454;N-(2,3-epoxy-propan-1-yl)phthalimide;(PHTHALIMIDOMETHYL)OXIRANE [HSDB];AC-25869;BP-12186;SMR001547505;SY012416;SY045476;SY058949;LS-109469;CS-0020844;FT-0601280;FT-0686960;FT-0771783;2-(2,3-epoxypropyl)isoindole-1,3(2H)dione;EN300-29534;N-(2,3-Epoxypropyl)phthalimide, >=95.0%;2-((OXIRANYL)METHYL)ISOINDOLE-1,3-DIONE;2-(oxiranylmethyl)-1H-isoindole-1,3-(2H)-dione;A830245;J-522810;N-(2,3-Epoxypropyl)phthalimide, >=95.0% (GC);2-(2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione #;2-[[(2S)-oxiran-2-yl]methyl]isoindoline-1,3-dione;Q27292950;ETHYL2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLATE;Z285045542;2-[(oxiran-2-yl)methyl]-2,3-dihydro-1H-isoindole-1,3-dione

Suppliers and Price of N-(2,3-Epoxypropyl)phthalimide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-GlycidylPhthalimide
25mg
$ 65.00

SynQuest Laboratories
2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione
100 g
$ 312.00

SynQuest Laboratories
2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione
25 g
$ 152.00

Sigma-Aldrich
N-(2,3-Epoxypropyl)phthalimide ≥95.0%
10g
$ 141.00

Oakwood
N-Glycidylphthalimide 95%
5g
$ 25.00

Matrix Scientific
2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione 97%
25g
$ 155.00

Matrix Scientific
2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione 97%
100g
$ 485.00

Atlantic Research Chemicals
2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione 95%
50gm:
$ 388.80

Apolloscientific
2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione 97%
100g
$ 283.00

American Custom Chemicals Corporation
N-(2,3-EPOXYPROPYL)-ORTHO-PHTHALIMIDE 95.00%
1G
$ 648.81

Total 89 raw suppliers

Chemical Property of N-(2,3-Epoxypropyl)phthalimide Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:5.38E-05mmHg at 25°C
Melting Point:92-98 °C
Refractive Index:1.648
Boiling Point:347.4 °C at 760 mmHg
PKA:-2.24±0.20(Predicted)
Flash Point:163.9 °C
PSA：49.91000
Density:1.446 g/cm³
LogP:0.61930
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.058243149
Heavy Atom Count:15
Complexity:291

Purity/Quality:

99% ^*data from raw suppliers

N-GlycidylPhthalimide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Other Nitrogen Rings
Canonical SMILES:C1C(O1)CN2C(=O)C3=CC=CC=C3C2=O
Uses N-(2,3-Epoxypropyl)phthalimide is a reagent used for the simultaneous preparation of a primary amine and secondary alcohol.

Technology Process of N-(2,3-Epoxypropyl)phthalimide

There total 13 articles about N-(2,3-Epoxypropyl)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5428-09-1
3-phthalimido-1-propene

: 5455-98-1
2-oxiranylmethylisoindole-1,3-dione

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1016/S0960-894X(98)00565-4

Reference yield: 98.0%

: 19667-37-9,34839-11-7,148857-42-5,148857-44-7
2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

: 5455-98-1
2-oxiranylmethylisoindole-1,3-dione

Guidance literature:: With potassium fluoride supported on Celite; In acetonitrile; for 0.5h; regioselective reaction; Reflux;
DOI:10.1055/s-0030-1260961