N-methyl-N-nosyl-L-valine phenacyl ester

Base Information

• Chemical Name: N-methyl-N-nosyl-L-valine phenacyl ester
• CAS No.: 1208119-51-0
• Molecular Formula: C₂₀H₂₂N₂O₇S
• Molecular Weight: 434.47
• Mol file: 1208119-51-0.mol

Synonyms:N-methyl-N-nosyl-L-valine phenacyl ester

Chemical Property of N-methyl-N-nosyl-L-valine phenacyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-methyl-N-nosyl-L-valine phenacyl ester

There total 1 articles about N-methyl-N-nosyl-L-valine phenacyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + N-nosyl-L-valine phenacyl ester (1208119-44-1) → N-methyl-N-nosyl-L-valine phenacyl ester (1208119-51-0)

Guidance literature:

In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/jo901643f

Reference yield: 72.0%

N-methyl-N-nosyl-L-valine phenacyl ester (1208119-51-0) + (fluorenylmethoxy)carbonyl chloride (28920-43-6) → Fmoc-N-methylvaline (103478-58-6,84000-11-3)

Guidance literature:

N-methyl-N-nosyl-L-valine phenacyl ester; With sodium thiophenolate; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Inert atmosphere;

With sodium carbonate; In water; pH=9;

(fluorenylmethoxy)carbonyl chloride; In 1,4-dioxane; at 0 ℃;

DOI:10.1021/jo901643f

Reference yield: 70.0%

N-methyl-N-nosyl-L-valine phenacyl ester (1208119-51-0) → N-nosyl-N-methyl-L-valine

Guidance literature:

N-methyl-N-nosyl-L-valine phenacyl ester; With sodium thiophenolate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

With hydrogenchloride; water;

DOI:10.1021/jo901643f

upstream raw materials:

diazomethane

N-nosyl-L-valine phenacyl ester

Downstream raw materials:

Fmoc-N-methylvaline

Refernces