Triethylene glycol monomethyl ether

Base Information

• Chemical Name: Triethylene glycol monomethyl ether
• CAS No.: 112-35-6
• Molecular Formula: C7H16O4
• Molecular Weight: 164.202
• Hs Code.: 29094990
• European Community (EC) Number: 203-962-1
• ICSC Number: 1291
• NSC Number: 97395
• UNII: DN0P4Q4I16
• DSSTox Substance ID: DTXSID5026912
• Nikkaji Number: J22.128G
• Wikidata: Q27157604
• Metabolomics Workbench ID: 124675
• ChEMBL ID: CHEMBL1794613
• Mol file: 112-35-6.mol

Synonyms:TRIETHYLENE GLYCOL MONOMETHYL ETHER;112-35-6;m-PEG3-alcohol;2-(2-(2-Methoxyethoxy)ethoxy)ethanol;Methyltrioxitol;Methoxytriglycol;Dowanol TMAT;Methyltriglycol;2-[2-(2-Methoxyethoxy)ethoxy]ethanol;Methoxytriethylene glycol;3,6,9-Trioxa-1-decanol;Methyl triethylene glycol;Triglycol monomethyl ether;Triethylene glycol methyl ether;Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-;Triethylene glycolmonomethyl ether;mPEG3-OH;Methoxy triglycol;NSC 97395;3,6,9-trioxadecanol;HSDB 1001;m-PEG3-OH;EINECS 203-962-1;BRN 1700198;UNII-DN0P4Q4I16;2-[2-(2-methoxyethoxy)ethoxy]ethan-1-ol;Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-;DN0P4Q4I16;DTXSID5026912;CHEBI:84233;triethylene glycol monomethylether;Triethyleneglycol monomethyl ether;NSC-97395;2-(2-(2-methoxyethoxy)ethoxy)ethan-1-ol;2-[2-(2-Methoxy-Ethoxy)-Ethoxy]-Ethoxyl;EC 203-962-1;DTXCID506912;Methyl Triglycol;CAS-112-35-6;triethyleneglycolmonomethylether;MFCD00002875;TGME;Methyl-PEG3-alcohol;methoxytriethyleneglycol;TGY (CHRIS Code);METHOXY PEG-3;MPEG-3;PEG-3 METHYL ETHER;3,6,9-trioxadecane-1-ol;SCHEMBL15587;WLN: Q2O2O2O1;PEG-3 MONOMETHYL ETHER;triethyleneglycol monomethylether;CHEMBL1794613;MACROGOL 150 METHYL ETHER;NSC97395;PEG-3 METHYL ETHER [INCI];Tox21_201820;Tox21_303115;AKOS015915321;2-(2-(2-methoxyethoxyl)ethoxy)ethanol;DECAN-1-OL, 3,6,9-TRIOXA-;NCGC00164137-01;NCGC00164137-02;NCGC00257220-01;NCGC00259369-01;2-[2-(2-methoxyethoxy)-ethoxy]-ethanol;BP-21397;Etanol, 2-[2-(2-metoxietoxi) etoxi]-;LS-66854;Triethylene glycol monomethyl ether, 95%;TRIETHYLENE GLYCOL MONOMETHYL-ETHER;2-(2'-(2"-methoxy ethoxy)ethoxy)ethanol;HY-135796;CS-0114074;FT-0649849;T0709;C70224;EN300-108122;A802558;TRIETHYLENE GLYCOL MONOMETHYL ETHER [HSDB];J-002758;J-525081;Q27157604;Triethylene glycol monomethyl ether, purum, >=97.0% (GC)

Chemical Property of Triethylene glycol monomethyl ether

Chemical Property:

• Appearance/Colour: Colorless odorless liquid
• Vapor Pressure: <0.01 mm Hg ( 20 °C)
• Melting Point: -44oC
• Refractive Index: n20/D 1.439(lit.)
• Boiling Point: 233.9 °C at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 95.3 °C
• PSA: 47.92000
• Density: 1.021 g/cm³
• LogP: -0.34170
• Storage Temp.: Store below +30°C.
• Water Solubility.: Completely miscible in water
• XLogP3: -1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 164.10485899
• Heavy Atom Count: 11
• Complexity: 67.5

Purity/Quality:

99% ^*data from raw suppliers

Triethylene Glycol Monomethyl Ether ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Glycol Ethers (E Series)
• Canonical SMILES: COCCOCCOCCO
• Inhalation Risk: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C.
• Uses: Plasticizer intermediate. Triethylene glycol monomethyl ether can be used as a reagent and solvent for applications such as: modification of anthraquinone material for redox flow batteriespreparation of polymeric electrolyte for electrochemical devices,formation of the binary system of polyethylene glycol for absorption of silica.

Technology Process of Triethylene glycol monomethyl ether

There total 17 articles about Triethylene glycol monomethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

triethylene glycol benzyl methyl ether (249508-40-5) → triethylene glucol monomethyl ether (112-35-6,95507-80-5)

Guidance literature:

With hydrogen; palladium;

DOI:10.1039/c39900000911

Reference yield: 87.0%

3-Hydroxybenzyl alcohol (620-24-6) → triethylene glucol monomethyl ether (112-35-6,95507-80-5) + 3-Phenoxybenzyl alcohol (13826-35-2)

Guidance literature:

Reference yield: 85.0%

→ triethylene glucol monomethyl ether (112-35-6,95507-80-5)

Guidance literature:

upstream raw materials:

oxirane

methanol

2-methoxy-ethanol

triethylene glycol benzyl methyl ether

Downstream raw materials:

2,5,8,11,14,17,20-heptaoxahenicosane

2-[4-(2,4-Dichloro-phenoxy)-phenoxy]-propionic acid 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester

2-[4-(4-Chloro-phenoxy)-phenoxy]-propionic acid 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester

{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxymethylsulfanyl}-benzene

Refernces

• 1、 Lebedeva,Mazaev,Tret'yakov. "Synthesis of glycol ethers and their use for intensification of oil recovery". . p. 1415 - 1417. Retrieved 2001.
• 2、 Huang, Hong,Li, Dong-Mi,Wang, Weizhou,Chen, Yi-Chang,Khan, Khalid,Song, Song,Zheng, Yan-Song. "Effect of carboxylic acid on micelles of a neutral amphiphilic dendro-calix[4]arene". . p. 729 - 735. Retrieved 2012.
• 3、 Khan, Khalid,Lal Badshah, Syed,Ahmad, Nasir,Rashid, Haroon Ur,Mabkhot, Yahia. "Inclusion complexes of a new family of non-ionic amphiphilic dendrocalix[4]arene and poorly water-soluble drugs naproxen and ibuprofen". supporting information. . Retrieved 2017/06/08.